Table 8-2 Proteins Associated With Skeletal Muscle Flashcards
Myomesin
Cross-links thick filaments that are next to each other at M line.
Myosin II
Major protein of thick filament; its interactiob with actin hydrolyzes ATP and produces contraction
Titin
Forms an elastic lattice that anchors thick filaments to Z disks
C protein
Binds to thick filaments at the M line
G actin
Polymerizes to form thin filaments of F-actin; interaction of G-actin with myosin II assists in hydrolyzing ATP, resulting in contraction.
Tropomyosin
Occupies grooves of the thin filaments
Troponin
TnC Binds calcium
TnT Binds to tropomyosin
TnI Binds to actin, thus inhibiting actinmyosin interaction
a- Actinin
Anchors plus ends of thin filaments to Z disk
Nebulin
z disk protein that may assist a-actinin to anchor thin filaments to Z disk
Cap Z
Forms part of the Z disk and caps the plus end of the thin filament
Tropomodulin
Caps the minus end of the thin filament