Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Robbins Pathology Renal (Chaptr 20,21) > Table 20.5 > Flashcards

Table 20.5 Flashcards

1
Q

Postinfectious Glomerulonephritis frequently presents as which condition

A

Nephritic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the pathogenesis of Postinfectious Glomerulonephritis

A

Immune comple mediated, circulating or planted antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which condition will present the diffuse endocapillary proliferation with leukocytosis infiltration on light microscopy

A

Postinfectious Glomerulonephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which condition with sho Granular IgG and C3 in the GBM and mesangium, with the occasional IgA on fluorescence microscopy

A

Postinfectious Glomerulonephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How will Postinfectious Glomerulonephritis present with electron microscopy

A

Primary with subepithelial humps and deposits early in the disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Goodpasture syndrome will frequently present with which clinical feature

A

RPGN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the pathogenesis of Goodpasture syndrome

A

Anti GBM COL4-A3 antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which condition will present as extracapillary proliferation with crescents and necrosis on light microscopy

A

Goodpasture syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which condition will present with Linear IgG and C3 with fibrin in crescents under fluorescence microscopy

A

Goodpasture syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Membranous nephropathy will typically present with which clincal presentation

A

Nephrotic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the pathogenesis of Membranous nephropathy

A

In situ immune complex formation, with PLA2Rantigen for most cases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which condition will present with with diffuse capillary wall thickening under light microscopy

A

Membranous nephropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which condition with present with granular IgG and C3 diffusely under fluorescence microscopy

A

Membranous nephropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Minimal change disease will commonly present with which clinical presentation

A

Nephrotic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What condition will present with normal findings with some lipid in the tubules under light microscopy

A

Minimal change disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the presentation of Minimal change disease under fluorescence microscopy

A

None

17
Q

What is the presentation of Minimal change disease under EM

A

-Loss of foot processes with no deposits

18
Q

Focal segmental glomerulosclerosis normally presents as which clinical presentation

A

Nephrotic syndrome

19
Q

What is the pathogenesis of Focal segmental glomerulosclerosis

A

-Ablation nephropathy

20
Q

What condition presents as focal and segmental sclerosis and hyalinosis

A

Focal segmental glomerulosclerosis

21
Q

What conditions presents as focal IgM and C3 under fluorescence microscopy

A

Focal segmental glomerulosclerosis

22
Q

How does Focal segmental glomerulosclerosis present under EM

A

Loss of foot processes with epithelial denudation

23
Q

Membranoproliferative glomerulonephritis type 1 normally presents with which clinical feature

A

Nephrotic/nephritic syndome

24
Q

What is the pathogenesis of Membranoproliferative glomerulonephritis type 1

A

Immune complexes

25
Q

Which conditions presents with mesangial or membranoproliferation

A

Membranoproliferative glomerulonephritis type 1

26
Q

What condition will have IgG, C3, C1q, C4 under fluorescence microscopy

A

Membranoproliferative glomerulonephritis type 1

27
Q

Membranoproliferative glomerulonephritis type 2 will typically present with which clinical feature

A

Hematuria and chronic renal failure

28
Q

What is the pathogenesis of Membranoproliferative glomerulonephritis type 2

A

-Autoantibody, alternative complement pathway

29
Q

Which condition will present with mesangial proliferation with GBM splitting

A

Membranoproliferative glomerulonephritis type 2 aka dense deposit disease

30
Q

Which condition will present with C3 but no C1q or C4 under fluorescence microscopy

A

Membranoproliferative glomerulonephritis type 2, and dense deposit

31
Q

IgA nephropathy will typically present with which clinical feature

A

Recurrent hematuria and proteinuria

32
Q

Which condition will present with focal mesangial proliferative glomerulonephritis with mesangial widening

A

IgA nephropathy

33
Q

Which condition will Preston with IgA, IgG, IgM and C3 in the mesangium

A

IgA nephropathy

Robbins Pathology Renal (Chaptr 20,21) (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions