Table 20.5 Flashcards
Postinfectious Glomerulonephritis frequently presents as which condition
Nephritic
What is the pathogenesis of Postinfectious Glomerulonephritis
Immune comple mediated, circulating or planted antigen
Which condition will present the diffuse endocapillary proliferation with leukocytosis infiltration on light microscopy
Postinfectious Glomerulonephritis
Which condition with sho Granular IgG and C3 in the GBM and mesangium, with the occasional IgA on fluorescence microscopy
Postinfectious Glomerulonephritis
How will Postinfectious Glomerulonephritis present with electron microscopy
Primary with subepithelial humps and deposits early in the disease
Goodpasture syndrome will frequently present with which clinical feature
RPGN
What is the pathogenesis of Goodpasture syndrome
Anti GBM COL4-A3 antigen
Which condition will present as extracapillary proliferation with crescents and necrosis on light microscopy
Goodpasture syndrome
Which condition will present with Linear IgG and C3 with fibrin in crescents under fluorescence microscopy
Goodpasture syndrome
Membranous nephropathy will typically present with which clincal presentation
Nephrotic syndrome
What is the pathogenesis of Membranous nephropathy
In situ immune complex formation, with PLA2Rantigen for most cases
Which condition will present with with diffuse capillary wall thickening under light microscopy
Membranous nephropathy
Which condition with present with granular IgG and C3 diffusely under fluorescence microscopy
Membranous nephropathy
Minimal change disease will commonly present with which clinical presentation
Nephrotic syndrome
What condition will present with normal findings with some lipid in the tubules under light microscopy
Minimal change disease
What is the presentation of Minimal change disease under fluorescence microscopy
None
What is the presentation of Minimal change disease under EM
-Loss of foot processes with no deposits
Focal segmental glomerulosclerosis normally presents as which clinical presentation
Nephrotic syndrome
What is the pathogenesis of Focal segmental glomerulosclerosis
-Ablation nephropathy
What condition presents as focal and segmental sclerosis and hyalinosis
Focal segmental glomerulosclerosis
What conditions presents as focal IgM and C3 under fluorescence microscopy
Focal segmental glomerulosclerosis
How does Focal segmental glomerulosclerosis present under EM
Loss of foot processes with epithelial denudation
Membranoproliferative glomerulonephritis type 1 normally presents with which clinical feature
Nephrotic/nephritic syndome
What is the pathogenesis of Membranoproliferative glomerulonephritis type 1
Immune complexes
Which conditions presents with mesangial or membranoproliferation
Membranoproliferative glomerulonephritis type 1
What condition will have IgG, C3, C1q, C4 under fluorescence microscopy
Membranoproliferative glomerulonephritis type 1
Membranoproliferative glomerulonephritis type 2 will typically present with which clinical feature
Hematuria and chronic renal failure
What is the pathogenesis of Membranoproliferative glomerulonephritis type 2
-Autoantibody, alternative complement pathway
Which condition will present with mesangial proliferation with GBM splitting
Membranoproliferative glomerulonephritis type 2 aka dense deposit disease
Which condition will present with C3 but no C1q or C4 under fluorescence microscopy
Membranoproliferative glomerulonephritis type 2, and dense deposit
IgA nephropathy will typically present with which clinical feature
Recurrent hematuria and proteinuria
Which condition will present with focal mesangial proliferative glomerulonephritis with mesangial widening
IgA nephropathy
Which condition will Preston with IgA, IgG, IgM and C3 in the mesangium
IgA nephropathy
