table 17-6 Flashcards
1
Q
Gastrointestinal Carcinoid Tumors: Esophagus Fraction of GI carcinoids Mean patient age (yr) Location Size Secretory product(s) Symptoms Behavior Disease associations
A
1% Rare distal Limited data (size) Limited data (secretory products) Dysphagia, weight loss, reflux Limited data None
2
Q
Gastrointestinal Carcinoid Tumors: stomach Fraction of GI carcinoids Mean patient age (yr) Location Size Secretory product(s) Symptoms Behavior Disease associations
A
<10% 55 Body and fundus 1-2 cm, multiple; >2 cm, solitary Histamine, somatostatin, serotonin Gastritis, ulcer, incidental Variable Atrophic gastritis, MEN-I
3
Q
Gastrointestinal Carcinoid Tumors: Proximal Duodenum Fraction of GI carcinoids Mean patient age (yr) Location Size Secretory product(s) Symptoms Behavior Disease associations
A
<10% 50 Proximal third, peri-ampullary 0.5-2 cm Gastrin, somatostatin, cholecystokinin Peptic ulcer, biliary obstruction, abdominal pain Variable Zollinger-Ellison syndrome, NF-1, sporadic
4
Q
Gastrointestinal Carcinoid Tumors: Jejunum and Ileum Fraction of GI carcinoids Mean patient age (yr) Location Size Secretory product(s) Symptoms Behavior Disease associations
A
>40% 65 Throughout <3.5 cm Serotonin, substance P, polypeptide YY Asymptomatic, obstruction, metastatic disease Aggressive None
5
Q
Gastrointestinal Carcinoid Tumors: Appendix Fraction of GI carcinoids Mean patient age (yr) Location Size Secretory product(s) Symptoms Behavior Disease associations
A
<25% All ages Tip 0.2-1 cm Serotonin, polypeptide YY Asymptomatic, incidental Benign None
6
Q
Gastrointestinal Carcinoid Tumors: Colorectum Fraction of GI carcinoids Mean patient age (yr) Location Size Secretory product(s) Symptoms Behavior Disease associations
A
<25% 60 Rectum > cecum >5 cm (cecum); <1 cm (rectum) Serotonin, polypeptide YY Abdominal pain, weight loss, incidental Variable None