Table 13-5 Adverse Effects Flashcards
Enalapril
cough, angioedema, renal failure, hyperkalemia, neutropenia, and proteinuria.
Enalapril class
(Ace-inhibitor)
Lisinopril-
cough, angioedema, renal failure, hyperkalemia, neutropenia, and proteinuria.
Lisinopril class
(Ace-inhibitor)
Cozaar / Losartan se’s -
Similar to ACE inhibitors, but do not cause cough
Cozaar / Losartan class
(Angiotensin-Receptor Antagonists) (ARBs)
Diovan/ Valsartan drug class
(Angiotensin-Receptor Antagonists) (ARBs)
Diovan/ Valsartan
Similar to ACE inhibitors, but do not cause cough
Atenolol
Metoprolol
Propranolol
Fatigue; depression; bradycardia; decreased exercise tolerance; congestive heart failure; aggravate peripheral arterial insufficiency; aggravate allergic reactions; bronchospasm; mask symptoms of and delay in recovery from hypoglycemia; Raynaud phenomenon; insomnia; vivid dreams or hallucinations; acute mental disorder; impotence; increased serum triglycerides.
Atenolol class
(Beta blocker)
Selective B1
Metoprolol class
Beta Blocker
Selective B1
Propranolol class
Beta blocker
Non selective
Coreg /Carvedilol
Similar to other β-adrenergic blocking drugs, but more orthostatic hypotension; no effect on serum lipids.
Coreg class
Beta-blocker
Non selective a1, b1, b2
Labetalol (generic) -
Similar to other β-adrenergic blocking drugs, but more orthostatic hypotension; no effect on serum lipids
Labetalol (generic) class -
Beta-blocker
non selective a1, b1, b2
Nebivolol (Bystolic)
Vasodilator due to nitric oxide–mediated action
Nebivolol (Bystolic) class:
Beta-blocker
selective b1
Lasix –
(Loop diuretic)
Dehydration; circulatory collapse; hypokalemia; hyponatremia; hypomagnesemia; hyperglycemia; metabolic alkalosis; hyperuricemia; blood dyscrasias; rashes; lipid changes as with thiazide-type diuretics.
Torsemide –
(Loop diuretic)
Dehydration; circulatory collapse; hypokalemia; hyponatremia; hypomagnesemia; hyperglycemia; metabolic alkalosis; hyperuricemia; blood dyscrasias; rashes; lipid changes as with thiazide-type diuretics.
Spironolactone –
(Aldosterone Antagonists)
Hyperkalemia; hyponatremia; mastodynia; gynecomastia; menstrual abnormalities; GI disturbances; rash.
Cardizem & Verapamil –
Dizziness; headache; edema; constipation (especially verapamil); AV block; bradycardia; heart failure; lupus-like rash.
Cardizem class
Calcium channel blocker
Verapamil class
Calcium ch blocker
Norvasc / Amliodipine
Nicardipine :
Dizziness; headache; peripheral edema (more than with verapamil and diltiazem; more common in women); flushing; tachycardia; rash; gingival hyperplasia.
Norvasc / Amliodipine
Nicardipine class:
Dihydropyridines (CCB)
Prazosin / Minipress
Syncope with first dose; dizziness and vertigo; headache; palpitations; fluid retention; drowsiness; weakness; anticholinergic effects; priapism.
Prazosin / Minipress class
a1 / (α-Adrenergic Blockers)
Clonidine –
CNS reactions similar to methyldopa, but more sedation and dry mouth; bradycardia; heart block; rebound hypertension (less likely with patches); contact dermatitis from patches.
Clonidine class
a2 / (Central α-Adrenergic Agonists)
Mehyldopa class and adverse effects
(Central α-Adrenergic Agonists)
Sedation but not as much as Clonidine
Mehyldopa class
Central α-Adrenergic Agonists
Hydralazine –
Tachycardia; aggravation of angina; headache; dizziness; fluid retention; nasal congestion; lupus-like syndrome; hepatitis
Hydralazine class
(Direct Vasodilators)
peripheral arterial dilation
Minoxidil –
Tachycardia; aggravation of angina; marked fluid retention; pericardial effusion; hair growth on face and body.
Minoxidil class
(Direct Vasodilators)
drug known for hair growth:
minoxidil
