T1D Flashcards

1
Q

Islet autoantibodies

A

GAD65 and IA2

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2
Q

Classic triad of symptoms

A

Polyuria, polydipsia, weight loss

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3
Q

Non-obese, gradual onset, antibody positive, don’t initially require insulin

A

LADA

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4
Q

DIDMOAD

A

Diabetes insipidus
Diabetes mellitus
Optic atrophy
Deafness

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5
Q

Formula for insulin requirements

A

0.3 x body weight, divided 50% basal and 50% bolus

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6
Q

Triad of DKA

A

Acidosis + hyperglycaemia + ketosis

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7
Q

Management of DKA

A

Fluid resus with 0.9% saline
Replace insulin and potassium
Switch to 5% dextrose once glucose

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