T1 L16: Transgender healthcare and hormone therapy Flashcards

1
Q

What is a GIC?

A

A gender identity clinic

It provides counselling, psychotherapy, psychological support, speech and language therapy, endocrinology, and surgery

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2
Q

What are the effects of Oestrogen treatment?

A

Hair: Some effect on facial hair, more effect on body hair, no effect on lost scalp hair but can prevent further loss

Breasts: Can expect 1 cup size smaller than mothers

The maximum achievement is after 2 years of treatment and higher doses don’t result in greater effects

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3
Q

How is Oestrogen treatment administered?

A

Oral or transdermal through patches/gel

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4
Q

When would a transgender patient stop taking oestrogen treatment?

A

The treatment is individualised but they don’t stop at the normal age of menopause

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5
Q

What is the effect of a GnRH analogue as an endocrine therapy for transgender patients?

A

It suppresses testosterone

IM injection every 3 months but isn’t required after a gonadectomy

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6
Q

What are the effects of Testosterone treatment?

A

Hair: male-pattern hair growth and scalp hair loss dependent of genetics

The maximal effect is after 5 years

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7
Q

How is Testosterone treatment administered?

A

IM injection every 3 weeks or 3 months or a gel can be given

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8
Q

Why do transgender people getting testosterone treatment not need a GnRH analogue?

A

Because testosterone treatment usually supresses menstruation

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9
Q

What are the risks of Oestrogen treatment?

A

Venous thromboembolism risk increased so smoking and obesity is advised against

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10
Q

What are the risks of Testosterone treatment?

A

Risk of polycythaemia so haemoglobin and haematocrit is monitored. This risk is greater in smokers

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11
Q

Why do Trans-men need to be put on contraception?

A

Testosterone treatment is teratogenic

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12
Q

What are trans-women screened for throughout their life?

A
  • Mammography from age 50 once on hormone treatment for 5 years
  • DEXA (bone density scan) at 60 but sooner if there are other risk factors for osteoporosis
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13
Q

What are trans-men screened for throughout their life?

A
  • Cervical and breasts screening as for XX unless they have been surgically removed
  • 2 yearly endometrium scans unless surgically removed
  • DEXA (bone density scan) after 60
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14
Q

What is the procedure for adolescents wanting to undergo trans-gender therapy?

A

It’s a specialist subject.

GnRH analogues are given to delay puberty and decisions are made about hormone therapy

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15
Q

What is Turner syndrome?

A

Caused by Monomy X

It causes developmental issues to do with puberty Eg. ovaries don’t develop, no puberty

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16
Q

What is androgen-insensitivity syndrome?

A

These people have a Karyotype of XY but their body doesn’t respond as well to androgen because of a lack of receptors to them so they are phenotypically female with male genital and a blind vagina.

Hormone levels are that of XY