T cells and cellular Immune response

Question 1

What do Lymphocytes require ?

Answer 1

activation before they can respond to antigens

Question 2

How do T cells become activated

Answer 2

requires an encounter with an antigen-presenting cell (accessory cell, APC), such as a B cell or macrophage, that has already encountered and phagocytized the antigen

Question 3

What do Macrophages acting as APCs do?

Answer 3

digest the pathogen, and display the antigenic fragments on their own cell membrane, complexed with special proteins called major histocompatibility complex (MHC) proteins

Question 4

What MHC proteins help T cells to do?

Answer 4

recognize displayed antigens

Question 5

What happens when T cells recognise and bind to antigenic fragments that match their receptors

Answer 5

They become activated?

Question 6

What is Cellular immune response or cell-mediated immunity

Answer 6

response through cell-to-cell contact, as activated T cells interact directly with antigen-bearing cells

Question 7

What do T cells also synthesize and secrete?

Answer 7

cytokines (such as interleukins and colony stimulating factors) that enhance cellular responses to antigens

Question 8

What do Some T cells secrete

Answer 8

toxins, growth-inhibiting factors, or interferon