T-Cell Immunity I (Dr. Robinson) Flashcards
1
Q
Which of the following cells does NOT secrete IFN-gamma? A. Th1 B. NK cells C. Activated CD8 D. Gamma-delta T cells E. Th2
A
E. Th2 does not secrete IFN-gamma
2
Q
Which cytokine AMPLIFIES TMMI? A. IL12 B. IL4 C. IFN-gamma D. IL6
A
C. IFN-gamma
3
Q
Which is a powerful activator of macrophages, and is a signature of an ongoing Th1 reaction? A. IFN-gamma B. IL12 C. IL18 D. All of the above
A
A. IFN-gamma
4
Q
What correctly describes IL12? A. Critical INITATION cytokine for Th1 rxn B. Critical GROWTH cytokine for Th1 rxn C. Signature cytokine of ongoing Th1 rxn D. Powerful activator of macrophages
A
A.
5
Q
What correctly describes IL2? A. Critical INITATION cytokine for Th1 rxn B. Critical GROWTH cytokine for Th1 rxn C. Signature cytokine of ongoing Th1 rxn D. Powerful activator of macrophages
A
B.
6
Q
intracellular or complex pathogen. DCs will secrete which cytokine to initiate the appropriate T-cell response? A. IL4 B. IL12 C. IL6 D. IL23
A
B. IL12
7
Q
Extracellular pathogen. DCs will secrete which cytokine to initiate the appropriate T-cell response? A. IL4 B. IL12 C. IL6 D. IL23
A
A. IL4
8
Q
IL12s best friend
A
IL18
9
Q
Which does NOT have CD3 A. Th1 B. Th2 C. NK D. NKT
A
C.
10
Q
IFNgamma
a. increases MHCII on APC
B. etc.
A
etc.
11
Q
email dr. robinson
A
is IFNgamma “activating” or is IL12?
12
Q
Which is NOT pro-inflammatory cytokine? A. IL-1 B. IL-6 C. IL-8 D. TNF-alpha E. IFN-gamma
A
E. IFN-gamma
13
Q
Which cytokine is NOT secreted by DC's, to promote a Th17 response? A. IL23 B. IL12 C. IL6 D. TGF-beta
A
C. IL6
14
Q
Pick out the inflammatory cytokine secreted by Th17 cells: A. IL17 B. IL23 C. IL4 D. IFN-gamma
A
C. IL17
15
Q
Which of the following T-cells is absolutely DEPENDENT on IL-2 for survival? A. Th1 B. Th2 C. Treg D. Th17
A
C. Treg
