Systems Biology - Lecture 3

Question 1

Emergent Properties

Answer 1

• collection or complex system has, but which the individual members do not have
• unique despite genetic similarity to other species and other humans
• Whole is greater than the some of individual components

Question 2

7 Characteristics of Life

Answer 2

1. Cellular organization
2. Ability to reproduce
3. Growth and development
4. Energy use (metabolism)
5. Maintain Homeostasis
6. Responsive to the environment
7. Pass traits to offspring

Question 3

Central Nervous System

Answer 3

Brain and Spinal Cord

Question 4

Peripheral Nervous System

Answer 4

Somatic (voluntary) Nervous System and Autonomic (Involuntary) Nervous System

Question 5

Endocrine System

Answer 5

• Endocrine Tissues and Exocrine Glands
• Hormones
  (mediators and monitoring communication)

Question 6

Support and Defense System

Answer 6

immune cells (Support, movement, repair)

Question 7

Properties of the control and communication network (CCN)

Answer 7

• Controls of all systems and individual organs, including itself
• Always on
• entire body
• Information flow is via chemical-based, cell-cell communication

Question 8

CCN is the integrator of inputs

Answer 8

1. Genetics (health, disease and aging)
2. Environment
3. Lifestyle (healthcare and lifestyle)

Question 9

CCN is the integrator of outputs

Answer 9

7 dimensions of health (spiritual, physical, mental, social, emotional, environmental and occupational)

Question 10

2 compromised function/structure of the CCN

Answer 10

• Abnormal function ex. Diabetes, cancer, depression and ADHD
• Reduced function ex. Alzheimer’s, diminished touch sensitivity and impaired wound without healing

Question 11

Integrated approach to health, disease and aging

Answer 11

P4 medicine - personalized, predictive, preventive and participatory