Systemic sclerosis

Question 1

Patient presents with scleroderma affecting face and distal limbs
anti-centromere antibodies Positive

Also presents with the following deatures

Calcinosis, Raynaud’s phenomenon, oEsophageal dysmotility, Sclerodactyly, Telangiectasia

Answer 1

Limited Cutaneous Systemic Sclerosis (LCSS)

Question 2

Patient presents with trunk and proximal limbs scleroderma
Antibody titre +ve for anti scl-70 antibodies
Auscultation of chest reveal bibasal fine inspiratory crackles
hypertension
On ACE inhibitor

Answer 2

Diffuse cutaneous systemic sclerosis