Systemic Mycoses Flashcards
fungal diseases that may affect
internal organs and may disseminate to multiple sites of
the body
Systemic mycoses
Systemic mycoses is some times known as?
Deep mycoses
Systemic mycoses occur in three disease forms:
acute self limited pulmonary (asymptomatic to
severe)
chronic (pulmonary or disseminate)
disseminated
Source of infection
Humans
Animals
The agents of subcutaneous and systemic mycoses,
however, are normally _____________ growing in the soil.
saprophytic fungi
Primary source of infection
Soil
Humans acquire these mycoses only when the spores of the soil organisms are either ______ or _____________ through a break in the skin.
inhaled, introduced in to the body
Systemic fungi includes:
Blastomyces dermatitis (blastomycosis)
Coccidioides immitis (coccidioidomycosis)
Histoplasma capsulatum (Histoplasmosis)
Paracoccidioides brasiliensis (paracoccidioidomycosis)
It refers to the disease caused by the
endemic, saprophytic, dimorphic fungus Blastomyces
dermatitidis.
Blastomycosis
Blastomycosis grows at what temperature as a ______ or ______ mold grows within the host at ______ as _______, _______ yeast like cells?
Room temp, white or tan, 37 degree celcius, budding, round
Blastomycosis is endemic in?
South Eastern and South Central states of North America, along the Mississippi
and Ohio River
Blastomycosis source of infection.
Streams or river with high content of moist soil enriched with organic debris and/or rotting wood.
Blastomycosis is acquired via?
inhalation of conidia
After ___ to ___ days an acute pulmonary disease indistinguishable from a bacterial pneumonia may occur.
30 to 40
In blastomycosis, at least ____ of primary infections are
asymptomatic
50%
In most cases the blastomycosis manifest during a chronic and
indolent phase that may affect the:
lungs
skin
bones
genitourinary tract
reticuloendothelial system
Symptoms of blastomycosis patients:
self-limited pneumonia
fever productive cough
myalgia
malaise
Form of infection by blastomycosis: even though it may resolve without treatment; however treatment is often used.
Acute pulmonary blastomycosis
Form of infection by blastomycosis: usually has granulomatous lesions in the upper lobe often misdiagnosed as carcinoma.
Chronic pulmonary blastomycosis
Form of infection by blastomycosis: is a progressive disease that follows hematogenous spread from unresolving pulmonary lesions by macrophages to remote sites, most commonly skin and bones
Disseminated blastomycosis
