Systemic Mycoses

Question 1

fungal diseases that may affect
internal organs and may disseminate to multiple sites of
the body

Answer 1

Systemic mycoses

Question 2

Systemic mycoses is some times known as?

Answer 2

Deep mycoses

Question 3

Systemic mycoses occur in three disease forms:

Answer 3

acute self limited pulmonary (asymptomatic to
severe)
chronic (pulmonary or disseminate)
disseminated

Question 4

Source of infection

Answer 4

Humans
Animals

Question 4

The agents of subcutaneous and systemic mycoses,
however, are normally _____________ growing in the soil.

Answer 4

saprophytic fungi

Question 5

Primary source of infection

Answer 5

Soil

Question 6

Humans acquire these mycoses only when the spores of the soil organisms are either ______ or _____________ through a break in the skin.

Answer 6

inhaled, introduced in to the body

Question 7

Systemic fungi includes:

Answer 7

Blastomyces dermatitis (blastomycosis)
Coccidioides immitis (coccidioidomycosis)
Histoplasma capsulatum (Histoplasmosis)
Paracoccidioides brasiliensis (paracoccidioidomycosis)

Question 8

It refers to the disease caused by the
endemic, saprophytic, dimorphic fungus Blastomyces
dermatitidis.

Answer 8

Blastomycosis

Question 9

Blastomycosis grows at what temperature as a ______ or ______ mold grows within the host at ______ as _______, _______ yeast like cells?

Answer 9

Room temp, white or tan, 37 degree celcius, budding, round

Question 10

Blastomycosis is endemic in?

Answer 10

South Eastern and South Central states of North America, along the Mississippi
and Ohio River

Question 11

Blastomycosis source of infection.

Answer 11

Streams or river with high content of moist soil enriched with organic debris and/or rotting wood.

Question 12

Blastomycosis is acquired via?

Answer 12

inhalation of conidia

Question 13

After ___ to ___ days an acute pulmonary disease indistinguishable from a bacterial pneumonia may occur.

Answer 13

30 to 40

Question 14

In blastomycosis, at least ____ of primary infections are
asymptomatic

Answer 14

50%

Question 14

In most cases the blastomycosis manifest during a chronic and
indolent phase that may affect the:

Answer 14

lungs
skin
bones
genitourinary tract
reticuloendothelial system

Question 15

Symptoms of blastomycosis patients:

Answer 15

self-limited pneumonia
fever productive cough
myalgia
malaise

Question 16

Form of infection by blastomycosis: even though it may resolve without treatment; however treatment is often used.

Answer 16

Acute pulmonary blastomycosis

Question 17

Form of infection by blastomycosis: usually has granulomatous lesions in the upper lobe often misdiagnosed as carcinoma.

Answer 17

Chronic pulmonary blastomycosis

Question 18

Form of infection by blastomycosis: is a progressive disease that follows hematogenous spread from unresolving pulmonary lesions by macrophages to remote sites, most commonly skin and bones

Answer 18

Disseminated blastomycosis