Systemic Inflammatory Response Syndrome

Question 1

What is SIRS?

Answer 1

It is a systemic inflammatory response and a severe immune response that involves the total body

Does NOT necessarily have to be an infection

Question 2

What are clinical manifestations of SIRS?

Answer 2

1. Systemic wide vasodilation–> fluid leaking out of vessels (edema)
2. Low BP
3. Fever
4. Elevated WBC
5. Poor perfusion because tissues are not getting oxygen, glucose, or nutrients due to the leakage

Question 3

What are the risk factors of SIRS?

Answer 3

BAIT PI

1. Burns
2. Anti inflammatory disorder
3. immunosuppressed patient such as chemotherapy patients
4. Trauma
5. Pancreatitis
6. IV drug users

Question 4

What is DIC and how is it treated?

Answer 4

Disseminated intravascular coagulation or DIC is a complication of SIRS and is the end stage of SIRS

treat DIC with heparin