Systemic Disease - Acquired Conditions Flashcards
what kind of bacteria is in the periodontal pocket?
pathogenic anerobic
list 3 types of host inflammatory cells released in inflammed perio pocket
IL-1
TNFa
PGE2
what causes link between periodontal disease and systemic chronic disease?
pro-inflamm mediators and perio bacteria leaking into systemic bloodstream
give the 3 groups of systemic diseases
systemic disorders that:
1. have a major impact on loss of peirodontal tissues by influencing periodontal inflammation - “perio as a manifestation of systemic disease”
- influence the pathogenesis of peiro disease
- result in loss of perio tissues independent of periodontitis
list diseases that have major impact on loss of periodontal tissues by influencing periodontal inflammation
Trisomy 21 - cardiac defects, immune defects, abnormal collagen synthesis
Papillon-lefevre - hyperkeratosis on hands/feet, severe perio soon after eruption and early loss of deciduous
Cyclic neutropenia - oral ulceration and rapid peiro destruction associated w/ low neurtophil nums, ulceration & necrosis of gingival margin
Ehlers danlos syndrome - excessive joint motility, hyperextensible skin, cardiac valve defects
Hypophosphatasia - abnormal mineralisation of bones and teeth, abnormal cementum so premature loss of baby teeth
what type of ehlers danlos syndrome is associated w/ high bleeding tendancy & grade c perio?
bleeding tendency = type 4
grade c perio = type 8
name a periodontal condition associated w/ HIV - 2 diseases within this?
necrotising periodontal disease (NPD) - necrotising gingivitis & necrotising periodontitis
how does HIV associated NP & NG present? increase chance of/response to tx?
clinically identical to non-HIV associated NP/NG
but inc chance of progression to more severe lesions
poorer response tot x
what is the most severe outcome of NP?
necrotising stomatitis
how does bacteria compare between HIV associated NPD and regular NPD?
similar bacteria though candida albicans often isolated in HIV associated NPD
why are there not always deep pockets in NP? what is an important feature of NP?
as there is rapid hard and soft tissue loss
severe deep pain localised to jaw bone
list tx options for HIV associated NP
conventional debridement
remove necrotic tissue/bone sequestrae under LA
oral metranidazole 200-400mg 3x daily for 7 days
2x a day chlorohexadine MW
list conditions of group 2 - systemic disorders that influence pathogenesis of perio disease (risk factors or disease modifiers)
diabetes melitus
obesity
osteoperosis
arthritis - RA & OA
emotional stress & depression
list conditions involved in group 3 - systemic conditions that result in loss of perio tissues independent of periodontitis (affect perio supporting tissues)
oral squamous cell carcinoma
odontogenic tumours
giant cell granulomas
systemic sclerosis (scleroderma)
