Systemic

Question 1

Fatigue, depression, weakness, hypotension, nausea, anorexia, weight loss, patchy oral mucosal pigmentation

Answer 1

Addison’s disease

Hypoadrenocorticism

Question 2

45 yo female w/ weight gain, moon facies, buffalo hump, hirsutism, muscle wasting, weakness, hyperglycemia, hypertension, depression. Most common cause of this condition?

Answer 2

Steroids

Cushings syndrome

Question 3

42 year old male presents w/ headache, visual disturbances, course facial features, mandibular prognathism, spaced teeth, macroglossia, and enlarged hands. Most likely cause?

Answer 3

Acromegaly

Question 4

34 yo female presents with broken tooth. Nervous. Tachycardia, tremor, warm skin, diaphoresis, exophthalmos, and a goiter. What do these findings suggest?

Answer 4

Hyperthyroidism

Grave’s disease - thyrotoxicosis

Question 5

52 yo female w/ puffy facial features, macroglossia, dry course hair, a husky voice, bradycardia. Complains of fatigue and office is too cold. What do these findings indicate?

Answer 5

Myxedema

Hypothyroidism

Question 6

9 yo female w/ round puffy facial features, macroglossia, delayed dental development, short stature, and reduced intelligence

Answer 6

Cretinism

Hypothyroidism

Question 7

Oral and maxillofacial complications of diabetes mellitus?

Answer 7

Xerostomia
Periodontal disease
Candidiasis and mucormycosis
Bilateral parotid enlargement

Question 8

36 yo female with erosive lichenoid oral lesions involving BM/gingiva/vermillion border. Photosensitive malar facial rash, low grade fevers, fatigue, myalgias, and arthritis. Biopsy shows lichenoid and perivascular lymphocytic infiltration. diagnosis?

Answer 8

Systemic lupus erythematous

Question 9

Elderly female with fatigue, shortness of breath, headache, a burning tongue, parasthesias of extremities, and ataxia. CBC shows megaloblastic anemia

Answer 9

Pernicious anemia

Question 10

50 year old female with fatigue, shortness of breath, headache, burning oral discomfort, and esophageal webs w/ dysphagia. CBC shows a microcytic hypochromic anemia

Answer 10

Oral-esophageal cancer

Plummer-Vinson syndrome

Question 11

Homeless elderly male alcoholic patient presents with diffuse petechial hemorrhages and marked gingival swelling/inflammation. These findings are most compatible with which one of the following conditions?

Answer 11

Vitamin C deficiency

Scurvy

Question 12

Child with coarse facial features, macroglossia, gingival hyperplasia, unerupted teeth with enlarged follicles, corneal clouding, reduced vision, growth retardation, skeletal deformities, stiff joints, and mental retardation

Answer 12

Mucopolysaccharidosis

Question 13

50 year old female with swelling of the right mandible. Radiographs show mandibular RL. Reduced bone volume, loss lamina dura. Biopsy shows CGC lesion

Answer 13

Hyperparathyroidism

Question 14

Child with premature loss of mandibular deciduous incisor teeth. Histologic exam of tooth shows lack of cementum on root surface. Diagnosis?

Answer 14

Hypophosphatasia

Question 15

Adolescent with mental retardation, spotty alopecia, cataracts, enamel hypoplasia, delayed dental development, and mucocutaneous candidiasis.

Answer 15

Hypoparathyroidism

Question 16

38 year old female w/ microstomia, dysphagia, and radiographic changes including diffuse widening of the PDL space and resorption of the posterior border of the mandibular ramus

Answer 16

Systemic sclerosis

Scleroderma

Question 17

Adult male with symptomatic cutaneous and oral findings (pics of rough areas in skin, papillary, skin lesions pigmented, oral lesions not as pigmented or not at all). Which of the following could be associated with this condition?

Answer 17

Acromegaly
Addisons
Gastroesophageal adenoma
Diabetes

Condition is acanthosis nigricans

Question 18

26 yo female with complaint of oral discomfort. Exam reveals diffusely erythematous oral mucosa with yellow slightly elevated, serpentine snail tract pustules on the palate, ventral tongue, buccal and labial mucosa

Answer 18

IBS

Pyostomatitis vegetans

Question 19

Hospitalized pt with diffuse oral burning oral discomfort, a bad taste in their mouth and multiple white plaques on tongue, floor of mouth, and buccal mucosa. Strong smell of ammonia detected on pts breath

Answer 19

Uremia

Uremic stomatitis

Question 20

Elderly male with macroglossia, multiple yellow-tan submucosal nodules on lateral tongue borders. Pt also complains of bone pain and fatigue. Tongue biopsy shows diffuse deposits of pink hyaline proteinaceous material that shows apple green birefringence under polarized light with congo red stain

Answer 20

Multiple myeloma with amyloidosis

Question 21

24 yo male with conjunctivus, urethritis, and arthritis following a chlamydia infection – can’t see, pee, and climb a tree. Has circinate balanitis and similar appearing oral lesions

Answer 21

Reiter’s Syndrome

Question 22

27 yo male with major oral aphthous ulcerations. Conjunctivus, genital ulcerations, and arthritis

Answer 22

Behcet’s Syndrome

Question 23

Multiple mucosal neuromas associated with:

Answer 23

Multiple endocrine neoplasia

Question 24

Strawberry gingivitis

Answer 24

Wegener’s granulomatosis

Question 25

32 yo black female with violaceous skin lesions, bilateral hilar adenopathy, pulmonary infiltrates, eye inflammation, periodontal bone loss, dry mouth, parotid enlargement. Biopsy shows non necrotizing granulomas

Answer 25

Sarcoidosis

Question 26

26-Gingival hyperplasia, ulcerated erythematous papules/nodules, thick creamy yellow plaques/exudate with bone loss and ocular conjunctivitis?

Answer 26

Plasminogen deficiency