Final Flashcards
Salivary gland malignancy by site
Sublingual gland 70-90%
Minor gland 50%
Submandibular gland 41-45%
Parotid gland 15-32%
Minor salivary gland malignancy by site
Retromolar trigone = 93%
Floor of mouth = 93%
Tongue = 80%
1 risk for Sjogren’s
40X increased risk of lymphoma
1 malignant salivary gland tumor
Mucoepidermoid carcinoma
1 salivary gland tumor
Pleomorphic adenoma
Most common location for SG tumors
Parotid 64-80%
Minor glands 9-23%
Submandibular gland 9-11%
Sublingual gland <1%
Episodic pain and swelling in Wharton’s duct
Sialolith
Foamy MP, lower lip swelling
Mucocele
Diagnostic criteria for Sjogren’s (4)
Ocular dryness (Schirmer test, Bengal staining)
Xerostomia (reduced saliva + focus score)
Serologic evidence of AI (RF, ANA, SS-A, SS-B)
Systemic AI
Craterlike ulceration of palate
Necrotizing sialometaplasia
1 benign tumor in children
Hemangioma-mesenchymal
Females
Parotid/palate
Myoepithelial cells
10-12% malignant transformation
Pleomorphic adenoma
Clear cells (pink cytoplasm means increased mitochondria)
Oncocytoma
Old man
Smoker
Parotid
Machine oil fluid
Warthin’s tumor
Old women
Upper lip mass
Canalicular adenoma
Painful mass parotid/palate/submandibular
Facial paralysis
Perineural invasion
Swiss cheese
Adenoid cystic carcinoma
Cancer of B lymphocytes
Form of NHL
Burkitt’s lymphoma
Virus for Burkitt’s lymphoma
EBV
Reed Sternberg cell
Hodgkins lymphoma
Virus for HL
EBV
1 intraoral lymphoma
Diffuse large BC NHL
Hemoglobin synthesis w/ point mutation in beta globin chain
Sickle Cell Anemia
Philadelphia chromosome
Chronic myeloid leukemia
Floating teeth (4 things)
Langerhans Cell Histiocytosis
Ewings Sarcoma
Lymphoma
Periodontitis
Birbeck granules
Langerhans Cell Histiocytosis
Plasma cell malignancy
Multiple myeloma
Gender predilection for MM
Male
Multiple punched out RL
Multiple myeloma
1 odontogenic cyst
Gingival cyst of the newborn
Rushton bodies
Radicular cysts
Neoplastic transformation (3 things)
Ameloblastoma
SSC
Mucoepidermoid carcinoma
Rests of Serres, dental lamina rests
OKC
Gorlin syndrome
Nevoid Basal Cell Carcinoma Syndrome
Gene of Gorlin syndrome
PTCH
Clear cells, glycogen rich
Lateral periodontal cyst
Variant of lateral periodontal cyst
Botryoid odontogenic cyst
Anterior maxilla, male, ghost cell keratin, unerupted tooth
Calcifying odontogenic cyst
Calcifying odontogenic cyst AKA ____
Gorlin cyst
Histologic variants of ameloblastoma
Follicular Plexiform Granular Desmoplastic Ameloplastic
Vickers-Gorlin criteria (4)
Palisaded columnar epithelial cells
Hyperchromatic nuclei
Reverse nuclear polarization
Sub-nuclear cytoplasmic vacuolization
Anterior maxilla, young female, impacted canine
Adenomatoid odontogenic tumor
AOT histology
Clinical appearance
Snow flake calcifications
Apical extension beyond CEJ
Driven snow calcifications
Calcifying epithelial odontogenic tumor
CEOT AKA ____
Pindborg tumor
CEOT histology
Liesegang ring
Concentric calcifications
Odontogenic myxoma histology
Bland spindled to stellate stromal cells Loose myxoid strma Mucopolysaccharide ECM Scant collagen Odontogenic epithelial rests
RP calcified mass
Attached to tooth root
Radiolucent rim
Benign cementoblastoma
Histology of benign cementoblastoma
Peripheral radiation
Simple type
WHO type
Granular cell type
Central odontogenic fibroma
Circumscribed apical RL
Non-expansile
Mandibular anterior
Periapical COD
1st-2nd decade
Male
Posterior mandible 70%
Painless slow growing
Ameloblastic fibroma
Contains mineralized dental matrix
Ameloblastic fibro-odontoma
Odontoma is a ____ malformation
Hamartomatous
Odontoma X-RAY
Mixed RP/RL
Freckles
Intestinal polyps
Puetz-Jeghers syndrome
+ Nikolsky sign
Auto-AB against epidermal cell glycoproteins, desmoglein 1/3
Pemphigus
Pemphigus histology
intraepithelial separation above basal cell layer
Pemphigus cells
Tzanck cells
Ocular lesions of MMP
Symblepharons Scarring Dryness Entropion Trichiasis
MMP oral lesion
Desquamative gingivitis
MMP histology
Split at underlying CT
Auto-AB IgG, C3
1 autoimmune blistering disease
Bullous pemphigoid
Wickham’s striae
Reticular lichen planus
Desquamative gingivitis (3)
MMP
Erosive lichen planus
Pemphigus vulgaris
LP histology
Saw-tooth rete ridges
Civatte bodies - degenerating keratinocytes
Aphthous ulcers associated disorders
Behcets Celiac Cyclic neutropenia IgA deficiency Immunocompromised IBS MAGIC PFAPA Sweet's
Aphthous ulcers histology
Central zone of ulceration
Fibrinopurulent membrane
Vascularity in CT
Inflammatory cells
Preceded by HSC and mycoplasma pneumoniae infections
Erythema multiforme
Early lesion for EM
Targetoid hand lesion
1 CT disorder in US
Lupus
Lupus DIF
IgM
IgG
C3 at BM
Strawberry gingivitis
Wegener’s granulomatosis
DX of Wegener’s granulomatosis
Anti-neutrophil cytoplasm antibodies ANCA
Leukocytoclastic vasculitis
Petechiae on hard palate
NUG
EBV
Mono
Variation of IBS
Pyostomatitis vegetans
2 syndromes of Sarcoidosis
Lofgrens
Heerfordts
1 oral “tumor”
Fibroma
Cobblestone appearance
Giant cell fibroma
Bad denture associated w/ ___
Epulis fissuratum
Pregnancy gingivitis, 7th month
Pyogenic granuloma
Associated w/ primary hypoparathyroidism
Peripheral giant cell granuloma
Radiographic cupping of underlying ridge
PGCG
Found at mental foramen
Traumatic neuroma
Benign tumor of Schwan cells
Neurilemoma
Tongue and buccal mucosa
Nerve sheath neoplasm
Neurofibroma
Von Recklinghousen’s disease
Neurofibromatosis Type I
Diagnostic criteria neurofibromatosis
Neurofibromas Café au lait Crowe's sign Lisch nodules Optic glioma
Marfonid body
Neuroma in eye
Upper eyelid everted
MEN
Pseudoepithelial hyperplasia
Granular cell tumor
Large round cells with granular eosinophilic cytoplasm
Congenital epulis
1 tumor of infancy
Hemangioma
Anterior tongue causing macroglossia
Lymphangioma
Small round blue cell tumor
Rhabdomyosarcoma
AIDS, HHV8
Kaposi’s Sarcoma