synthesis

Question 1

what happens when Br2 is added to an aromatic compound

Answer 1

(Bromine) would be decolourised/turn (from
orange/red/yellow/brown) to colourless
OR white precipitate/solid/emulsion (formed

Question 2

Mesalazine reacts with acids to form salts.Explain how mesalazine is able to react with acids.

Answer 2

Nitrogen electron pair OR nitrogen lone pair

accepts a proton/H+ 

Question 3

Suggest why these conditions were used, rather than the reaction mixture being distilled during the process. for primary alcohol

Answer 3

to ensure carboxylic acid is formed
OR prevents formation of aldehyde
OR distillation only makes the aldehyde


Question 4

Suggest an advantage of developing a synthetic route to oxandrolone starting from a natural steroid.

Answer 4

ensures correct chirality 

Question 5

Before any skin cream can be sold to the public, it must be tested to ensure it is safe to use.Suggest why.

Answer 5

To test for (adverse) side effects
OR to test toxicity
OR to test for irritation 

Question 6

Some artificial sweeteners commonly available many years ago have now been withdrawn from use.
Suggest why.

Answer 6

(adverse) side effects
OR toxicity
OR irritation 

Question 7

Explain what is meant by the term stereoisomers.

Answer 7

stereoisomers have the same structural formula
AND
different 3D arrangements 

Question 8

Explain why it is necessary for pharmaceutical companies to ensure that drugs and medicines are pure.

Answer 8

to ensure no side effects