synovial fluid Flashcards
Viscous fluid surround the _______
Diarthroses
Viscosity is due to polymerization of hyaluronic acid (produced
by___________
synoviocytes
non-inflammatory
clear,yellow fluid
good viscosity
WBC: <1000 uL
Neutro: <30%
similar to blood glucose
inflammatory
cloudy, yellow fluid
poor viscocity
WBC: 2000-75,000 uL
Neutro: >50%
decrease glucose level
possible antibodies
normal volume
<3.5 mL
leukocyte count of synovial:
<200 cells/uL
neutrophils in synovial:
<25% of the differential
GLUCOSE: PLASMA
DIFFERENCE
<10mg/dL lower than the blood
glucose level
TOTAL PROTEIN
<3mg/dL
order of tubes
- chemical exam
- microscopic exam
- microbiological exam
tip to prevent false decrease values by glycolysis
- examined after 1 hr
- preserved with SODIUM FLOURIDE
COLOR AND CLARITY for normal
colorless to pale yello
COLOR AND CLARITY: deeper yellow
inflammation
COLOR AND CLARITY: greenish-tinge
bacterial infection
COLOR AND CLARITY:red
traumatic tap or hemorragic athritis
COLOR AND CLARITY: turbid
wbc, synovial cell dibris, fibrin
COLOR AND CLARITY: milky
crystals
normal viscocity: forms a string on the tip of syringe:
4-6 mm long
hyaluronic acid level
0.3-0.4 g/dL
otherwise known as hyluronate polymerization tes
ropes test or mucin clot test
reagent for rope/mucin clot test
2 to 5% acetic acid
total normal leukocyte count of synovial
<200/uL
toal abnormal leukocyte count of synovial
> 100,000/uL;severe infection
diluting fluid
1.NSS with methylene blue
2. hypotomic saline (0.4%)
3. saline with saponin