synovial fluid Flashcards

1
Q

Viscous fluid surround the _______

A

Diarthroses

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2
Q

Viscosity is due to polymerization of hyaluronic acid (produced
by___________

A

synoviocytes

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3
Q

non-inflammatory

A

clear,yellow fluid
good viscosity
WBC: <1000 uL
Neutro: <30%
similar to blood glucose

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4
Q

inflammatory

A

cloudy, yellow fluid
poor viscocity
WBC: 2000-75,000 uL
Neutro: >50%
decrease glucose level
possible antibodies

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5
Q

normal volume

A

<3.5 mL

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6
Q

leukocyte count of synovial:

A

<200 cells/uL

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7
Q

neutrophils in synovial:

A

<25% of the differential

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8
Q

GLUCOSE: PLASMA
DIFFERENCE

A

<10mg/dL lower than the blood
glucose level

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9
Q

TOTAL PROTEIN

A

<3mg/dL

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10
Q

order of tubes

A
  1. chemical exam
  2. microscopic exam
  3. microbiological exam
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11
Q

tip to prevent false decrease values by glycolysis

A
  1. examined after 1 hr
  2. preserved with SODIUM FLOURIDE
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12
Q

COLOR AND CLARITY for normal

A

colorless to pale yello

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13
Q

COLOR AND CLARITY: deeper yellow

A

inflammation

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14
Q

COLOR AND CLARITY: greenish-tinge

A

bacterial infection

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15
Q

COLOR AND CLARITY:red

A

traumatic tap or hemorragic athritis

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16
Q

COLOR AND CLARITY: turbid

A

wbc, synovial cell dibris, fibrin

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17
Q

COLOR AND CLARITY: milky

18
Q

normal viscocity: forms a string on the tip of syringe:

A

4-6 mm long

19
Q

hyaluronic acid level

A

0.3-0.4 g/dL

20
Q

otherwise known as hyluronate polymerization tes

A

ropes test or mucin clot test

21
Q

reagent for rope/mucin clot test

A

2 to 5% acetic acid

22
Q

total normal leukocyte count of synovial

23
Q

toal abnormal leukocyte count of synovial

A

> 100,000/uL;severe infection

24
Q

diluting fluid

A

1.NSS with methylene blue
2. hypotomic saline (0.4%)
3. saline with saponin

25
wbc differential for MONOCYTE AND MACROPHAGE
65%
26
wbc differential for NEUTROPHILS
<25%
27
wbc differential for LYMPHOCYTES
<15%
28
RBC COUNT/TOTAL CELL COUNT
<2,000/uL
29
has vacuolated macrophage with ingested neutrophil
reiter cell
30
neutrophils that is dark, small,cytoplasmic granules consist of rheumatoid factor
Ragocyte
31
neutriphil: round body
LE cell
32
monocyte that have engulfed nuclear material
tart cell
33
resemble mesothelial cell
synovial lining cell
34
large, mononuclecated cell
cartilage cell
35
debris from metal and plastic joint prosthesis LOOK LIKE GROUND PEPPER
OCHRONOtic shards
36
monosodium urate/uric acid
APPEARANCE: needlike like SIGNIFICANCE: gout COMP.POLARIZED LIGHT: yellow Berefringence: negatice
37
calcium pyrophosphate
APPEARANCE: rhomboid square,rods, needle like SIGNIFICANT: pseudogout Birefrigence: positive
38
normal lactate
<250 mg/dL
39
normal glucose
<10 mg/dL
40
normal protein
<3 g/dL