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Syndrome paranéoplasique Flashcards

1
Q

Ganglionnopathie paraneoplasique

A

Anti Hu et anti crmp5

surface

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2
Q

myasthénie grave

A

anti Rach, antiMuSK, antiLRP4

surface

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3
Q

neuropathy autonomique : anticorps et cancer

A

anti RaCH, alpha-3 ganglionic , adenocarcinome

surface

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4
Q

anti récepteur AMPA : syndrome et cancers

A

encephalite limbique : tumeurs thymique, SCLC, cancer du sein

surface

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5
Q

NMO : anticorps et cancer associé

A

Anti aquaporine 4 : thymome, cancer du poumon, cancer du sein

surface

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6
Q

Neuromyotonie /syndrome de Morvan : anticorps et cancer

A

CASPR2 , thymome

surface

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7
Q

DPPX : syndrome clinique et cancer

A

encephalite bas grade, hyperexcitabilité SNC, syndrome du tronc cerebral, ataxie perte de poids et diarrhée, associé à néo hématologique

surface

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8
Q

Anti GABA A, syndrome et cancer

A

lésion cortical et sous cortical, status epileptique
thymome

surface

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9
Q

Anti GABA B : syndrome et cancer

A

encephalite limbique, status epileptique

SCLC

surface

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10
Q

anti Gly : syndrome et cancer

A

progressive encephalomyelitis with rigidity and myoclonus (PERM)

stiff person syndrome

Thymome

surface

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11
Q

IgLON5 : syndrome et cancer

A

Sleep disorders, symptômes bulbaire, désordre de la marche, peut mimer PSP

adenocarcinome

surface

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12
Q

convulsion dystonique brachiofaciale : anticorps et cancer

A

LGI1 : thymome (10%)

surface

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13
Q

anti mGlu receptor 1 : syndrome et cancer

A

ataxie
lymphome de hodgkin

surface

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14
Q

anti mGLu récepteur 5 : syndrome et cancer

A

syndrome ophelia (encephalite limbique)

lymphome de hodgkin

surface

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15
Q

anti NMDA : syndrome et cancer

A

psychose, convulsion, encephalopathi, dyskinésie orofaciale, hypoventilation

teratome ovarien

surface

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16
Q

anti PCA-Tr/DNER

A

cerebellar ataxia, brainstem encephalitis

lymphome de hodgkin

surface

17
Q

anti P/Q N-type voltage-gated calcium (syndrome et cancer)

A

lambert eaton, ataxie, SCLC

surface

18
Q

AGNA/SOX1 : syndrome et cancer

A

lamber eaton
sclc
intracellulaire

19
Q

2 anticorps du lambert eaton

A

P/Q type and N-type voltage gated calcium channels et agna/sox1

20
Q

antiamphiphysin syndrome et cancer

A

stiff person syndrome

cancer du sein
sclc

antigène intracellulaire

21
Q

anti Hu (anna-1) syndrome et cancer

A

neuronopathie sensitive, encephalite limbique, dysmotilité intestinale, ospsoclonus-myoclonus

neuroblastome, thymome, sclc

22
Q

anti-R1 (anna-2) syndrome et cancer

A

ospsoclonus-myoclonus (Adulte) dystonie de la machoire, laryngospasme, encephalite du tronc, ataxie

SCLC, cancer du sein

intracellulaire

23
Q

Anti CRMP-5/anti-cv2 SYNDROMES ET CANCER

A

Chorée, rétinopathie, myelopathie, neuropathie, encephalite

SCLC, thymome

24
Q

anti gad65 syndrome et cancer

A

stiff person syndrome
encephalite limbique
ataxie

SCLC

intracellulaire

25
Q

GFAP

A

méningoencephalitomyélite, oedeme disque otpique. peut coexsiter avec anti-NMDA et anti-AQ4

teratome

intracellulaire

26
Q

AntiGRAF1

A

rhombencephalite

cancer de l’ovaire

intracelullaire

27
Q

anti ITPR1 syndrome et cancer

A

anomalie MEO, ataxie

cancer du sein, cancer du poumon, néo hématologique

intracellulaire

28
Q

Kelch-like protiein 11

A

ataxie, rhombencephalite, incluant perte d’audition et vertige

seminome

intracellulaire

29
Q

Anti Ma1, Ma2

A

encephalite limbique, narcolepsy/cataplexy, rhombencephalite

cancer testiculaire (Ma2) ou tumeurs diverses

itnracellulaire

30
Q

anti neurochondrin

A

ataxie

cancer utérin

intracellulaire

31
Q

neuronal intermediate filament light

A

encephalopathy, ataxie, myelopathie

cancer neuroendocrinien (SCLC, carcinome cellule de meckel

intracellulaire

32
Q

anti PDE10A

A

encephalopathy
chorée
post-immune checkpoint-inhibitors

cancer du poumons, rein, pancreas

intracellulaire

33
Q

PCA-1/CDR2

A

ataxie

cancer ovaire, endomètre, trompe de fallope, sein

intracellulaire

34
Q

pca-2 (map1b

A

manifestation clinique diverse

SCLC

intracellulaire

35
Q

protéine kinase C

A

ataxie

cancer du poumon non petites cellules, ADNK hepatobilliaire

intracellulaire

36
Q

anti recoverin

A

retinopathi

SCLC

intracellulaire

37
Q

anti TRIM46

A

encephalite, ataxie

sclc

intracellulaire

38
Q

zic4

A

Ataxie

sclc

intracellulaire

Flashcards neuro (5 decks)

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