Syncope Flashcards
what is syncope
Transient loss of postural tone and consciousness caused by a period of inadequate cerebral perfusion. Episodes rarely last > 1 minute. Full recovery to baseline mental status without resuscitation, no postictal state.
Syncope ddx is very broad, but ___ and ___ causes are generally at the forefront
Cardiac
Neurologic
Cardiopulmonary ddx of snyncope
- Valvular Disease
- Arrhythmias - VT, VF, Torsades, Afib/flutter
- Brugada Syndrome
- 2nd / 3rd AV Heart Block
- WPW
- Aortic Dissection
- Heart Failure
- HCOM
- Pulmonary Embolism
- Myocardial Infarction
- Pacemaker dysfunction
- Carotid Sinus hypersensitivity
neurologic ddx for syncope
- Vasovagal (coughing, seeing blood, fear, defecation, valsalva)
- Subarachnoid Hemorrhage
- Stroke / TIA
- Seizure
- Narcolepsy
other ddx for syncope
- Anxiety
- Volume depletion (Vomiting, dehydration, sweating)
- Hemorrhage (GI bleed, ectopic pregnancy, abdominal trauma)
4 conditions/hx that are more likely syncope
- Reflex Syncope (Vasovagal - vasodilation / bradycardia)
- Orthostatic Syncope (Severe orthostatic hypotension) 5-24%
- Cardiac Arrhythmias
- Structural cardiopulmonary disease
6 conditions/hx that are not likely syncope
- Vertigo
- Seizure
- Narcolepsy (Loss of Consciousness) vs. Cataplexy (Loss of muscle tone)
- Traumatic Brain Injury (Concussion / Brain Bleeds)
- Intoxication
- Metabolic abnormalities - Hypoglycemia
syncope hx of Number, frequency, duration
- Multiple events with new onset - consider AV block
- Multiple events over many years - may be susceptible to vasovagal syncope
- Multiple episodes daily lasting multiple minutes - psychogenic possibility
Onset Activity of syncope
Extended prodrome - ?
No prodrome - ?
vasovagal
more concerning for cardiac
syncope hx of position?
- Supine - more significant for cardiac etiology
- Change in position - Orthostatic Hypotension (Can be multiple minutes after change)
- Upright - Reflex Syncope (Vasodilation +/- bradycardia)
what is reflex syncope?
Immediately after exercise, defecation or urination, coughing, swallowing, post-prandial, warm and crowded place, prolonged standing, fear, sight of blood, stress, abrupt neck movements.
preceding sx of syncope hx
Prodrome
- Lightheadedness
- Warmth or cold
- Sweating
- Palpitations
- Nausea - abdominal discomfort
- Blurred vision (blindness possible)
- Diminished hearing or tinnitus
- Pallor reported by observers
post event of syncope hx
- Continued nausea, pallor, diaphoresis often associated with Reflex Syncope
- True syncope is usually 1-2 minutes at most as the supine position restores cerebral perfusion
- Extended syncope - think seizure vs. psychogenic
Associated Signs and Symptoms of syncope hx
- Syncope in the presence of new/severe HA - rule out subarachnoid
- Chest pain or shortness of breath - Rule out PE, MI, HF
- Fever - Do sepsis workup if indicated. Consider COVID-19 infection (Some pts this is the only symptom)
Pre-existing Medical Conditions for syncope hx
- CAD, valvular disease, cardiomyopathy, congenital heart disease, previous cardiac surgery all at high risk for arrhythmias
- DM - risk for Orthostatic Hypotension d/t autonomic neuropathy and hypoglycemia
- Previous psych or drug use hx
- Seizure, stroke hx
what rhythm can cause pts to pass out?
torsades (QT prolongation)
common drugs that can cause QT prolongation
- Diuretics, Beta or Alpha Blockers, CCB (Non-DHP)
- MANY psych and neuro drugs, antiemetics, antiarrhythmics, antifungals, some antibiotics
what measurement of QTx is when concern for torsades
> 500
QTc >440 in Men
QTc> 460 in Women
Concerning hx factors for Cardiac etiology for syncope
- Absence of Prodrome
- Event during exertion or supine
- Associated with Chest Pain
- Family hx of sudden death
- Known structural heart disease
- Abnormal rhythm hx
General PE for syncope
- ABC’s with every ER patient
- Do they appear awake and alert at the time of examination
- Vital Signs
- O2 saturation, HR, BP, Temperature
— BP very low (Sepsis, Cardiac issue, Overdose, Late HF)
— BP very high (Stroke, HF, Anxiety)
Syncope - components of complete CARDIAC physical exam
- Murmurs
- Aortic Stenosis, Mitral regurgitation, Tricuspid Stenosis - Irregular or Bradycardic Rhythms
- Atrial Fibrillation, Significant PVCs
- Heart Blocks (Especially 3rd Degree)
- Symptomatic Bradycardia - Signs and Symptoms of Heart Failure
- Bilateral lower extremity swelling
- Increased JVD
- S3 / S4
syncope - components of complete neuro exam
- Mental Status
- Cranial Nerves
- Motor Strength
- Sensation
- Gait
- Reflexes
- Finger to Nose, Heel to Shin, Romberg, Pronator Drift
- Irregular exam would be cause for CT of brain
syncope - Evaluate for Head and Neck Trauma if appropriate:
- CT scan Canadian CT Rules and NEXUS Criteria if head or neck hit during fall
- Skin Turgor / Oral Mucosa / Volume Status
- Abdominal
- AAA - Pulsatile Mass
- Rectal exam for GI Bleed (FOBT only for non visible blood samples) - Any other exam that the history deems relevant
required w/u for syncope
EKG
Cardiac Monitor throughout stay
everything else - consider based on hx, age, RFs