Synaptic transmission Flashcards
what is the first step of synaptic transmission ?
an action potential travels down the axon to the pre synaptic nerve ending to vesicles which contain neurotransmitters
what is the second step of synaptic transmission ?
the vesicles fuse with the pre synaptic nerve ending and release the neurotransmitters into the synaptic cleft through a process called exocytosis
what is the third step of synaptic transmission ?
neurotransmitters diffuse across the synaptic cleft and bind to receptors on the post synaptic nerve ending
what is the fourth step of synaptic transmission if the neurotransmitter is excitory ?
bind to create a EPSP. This will increase the likelihood that the post synaptic neuron will create a new electrical impulse .
what is the fourth step if the neurotransmitter is inhibitory ?
bind to create a IPSP that decreases the likelihood that a post synaptic neuron will create a new electrical impulse .
what is the 5th step of synaptic transmission ?
excess neurotransmitters are taken up by the pre synaptic nerve ending (re-uptake)
what is the 6th step of synaptic transmission ?
enzymes are released to break down the remaining neurotransmitters
what is the 7th step of synaptic transmission ?
vesicles in the pre synaptic neuron are replenished with new and reused neurotransmitter ready for the next message
give three example of excitatory neurotransmitters and what they do ?
glutamate -important in learning and memory
norepinephrine-fight or flight
dopamine -gives feeling of pleasure , motivation and satisfaction and plays an important role in sleep
give three examples of inhibitory neurotransmitters and what they do ?
GABA- producing a calming effect
Serotonin - regulates mood
Dopamine- motivation and satisfaction and plays an important role in sleep
how do inhibitory and excretory neurotransmitters increase /decrease the likelihood of a active potential ?
change the electrical charge in the membrane of the post synaptic cell .
how does a post synaptic cell decide if its pos or neg ?
summation -add up IPSP and EPSP and see which is more