Synapses And Disease

Question 1

What is a synapse

Answer 1

Gap between neurones or effectors carrying an impulse

Question 2

What happens at a synaose

Answer 2

Action potential arrives at pre synaptic bulb
Volate gated ca+ open and diffuse
Vesicles with neurotransmitter fuse with pre-synaptic neurone relaing into synaptic cleft
Neurotransmitters diffuses and binds with na channels at post
Na channels open and enter post synaptic neurone
> na enters to reach threshold na voltage gates open and action potential occurs

Question 3

Why can’t impulse go backwards

Answer 3

Ca only found at axon terminal
Neurotransimmeters at axon terminal
Gates na only at dendrite

Question 4

L-dopa and parkinsons

Answer 4

Building bloack for dopamine neurotransmitters increases dopamine in synaptic cleft
Binds to receptors at post synaptic membrane as similar shape
Breaks down dopamine allowing it to stay in synaptic cleft