Synapses Flashcards
Synapses
Action potentials are transmitted between neurons and effectors, across synapses via the release of neurotransmitters.
When the neurotransmitter across the synaptic cleft, it interacts with the receiving membrane to cause a depolarisation that results in propagation of the nerve signal.
Steps of the strands mission at a synapse
Step 1: arrival of an action potential at the presynaptic Terri always causes an influx of calcium ions and includes the vesicles to release their neurotransmitter into the synaptic cleft
Step 2: the neurotransmitter diffuses across the synaptic cleft to receptors on the postsynaptic membrane. This delays the impulse transmission by about 0.5ms
Step 3: The neurotransmitter binds to the receptors on the postsynaptic membrane
Step 4: Ion channels in the membrane open, causing an influx of Na+. This response may or may not required to generate a nerve impulse.
Step 5: The neurotransmitter is deactivated by an enzyme located on the membrane. Components of the neurotransmitter are actively reabsorbed back into the synaptic knob, recycled and repackaged.
Neurotransmitter
A chemical signalling molecule.
Neurotransmitter maintain signals i the nervous system by binding to receptors on post-synaptic neurons and triggering electrical impulses
Excitatory neurotransmitters
They trigger depolarisation, increasing the likelihood of a response
Inhibitory neurotransmitters
They trigger hyper-polarisation, decreasing the likelihood of a response
Acetylcholine
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