Symposium: Anaemia

Question 1

what are the types of inherited red cell problems

Answer 1

• membrane problems eg hereditary spherocytosis
• haemoglobinopathy eg thalassemia or sickle cell disease
• metabolic eg G6PD deficiency

Question 2

where are the haemoglobin chains located

Answer 2

chromosome 11 and 16

Question 3

what is the blood film like in beta thalassaemia

Answer 3

microcytic hypochromic blood film

Question 4

clinical features of sickle cell anaemia

Answer 4

• anaema and jaunidice
• dactylitis
• splenic sequestration in children
• susceptibility to pneumococcal septicaemia