Lecture 7: Thrombosis Flashcards
1
Q
what is Virchow’s triad of thrombosis risks
A
- hypercoagutable state eg pregnancy
- endothelial injury eg drug users
- circulatory stasis eg surgery patients
2
Q
how is deep vein thrombosis diagnosed
A
doppler ultrasound
3
Q
examples of antithrombotic drugs
A
- warfarin
- heparin
- dabigatran
- rivaroxaban
4
Q
what does dabigatran do
A
oral direct thrombin inhibitor
5
Q
what does rivaroxaban do
A
oral direct factor Xa inhibitor
6
Q
what does aspirin inhibit
A
cyclo-oxygenase
7
Q
what does clopidogrel do
A
blocks ADP receptor
8
Q
what does dipyridamole do
A
inhibits phosphodiesterase
9
Q
what does prostacyclin do
A
stimulates adenylate cyclase
10
Q
what does warfarin do
A
- vitamin K antagonist
- prevents gamma carboxylation of factors II, VII, IX and X
