Sympathomimetics

Question 0

Norepinephrine receptor sensitivity and application

Answer 0

Sympathomimetic.
Alpha1=alpha2&raquo_space;beta 1. No beta 2 or D1
Hypotension but decreases renal perfusion!

Question 1

Epinephrine receptor sensitivity and application

Answer 1

Sympathomimetic.
B1 = B2 > alpha1=alpha2. No D1.
Trts anaphylaxis, glaucoma (open angle), asthma and hypotension.

Question 2

Isoproterenol receptor sensitivity and application

Answer 2

Sympathomimetic.
Beta1=beta2 only
Rare: AV BLOCK

Question 3

Dopamine receptor sensitivity and application

Answer 3

Sympathomimetic.
Low dose: D1
Medium dose: beta1&2
High dose: alpha1&2
Treats shock (renal perfusion), HF, inotropic and chronotropic; D1>beta>alpha.

Question 4

Dobutamine receptor sensitivity and application

Answer 4

Sympathomimetic.
Beta1»> beta2=alpha1&2
Treats HF, used for cardiac stress testing. Inotropic and chronotropic.

Question 5

Phenylephrine receptor sensitivity and application

Answer 5

Sympathomimetic.
Alpha 1»> alpha 2
Used to dilate pupils, vasoconstriction, and nasal decongestion.

Question 6

Ritodrine uses and action

Answer 6

Beta2 agonist which reduces premature uterine contractions.

Question 7

Metaproterenol receptor sensitivity and application

Answer 7

Sympathomimetic
Beta2»>beta1
Treats acute asthma.

Question 8

Albuterol receptor sensitivity and application

Answer 8

Sympathomimetic.
Beta2»beta1
Treats acute asthma

Question 9

Salmeterol receptor sensitivity and application

Answer 9

Sympathomimetic
Beta2»>beta1
Long term treatment of asthma

Question 10

Terbutaline receptor sensitivity and application

Answer 10

Sympathomimetic.
Beta2»>beta1
Reduces premature uterine contractions

Question 11

Amphetamine method of action and application

Answer 11

Indirect Sympathomimetic.
Indirect general agonist, releases catecholamine stores.

Treats narcolepsy, obesity, & ADD

Question 12

Ephedrine method of action and application

Answer 12

Indirect Sympathomimetic
Indirect general agonist, releases stored catecholamine.
Treats nasal decongestion, urinary incontinence, & hypotension

Question 13

Cocaine method of action and application

Answer 13

Indirect Sympathomimetic
Indirect general agonist, uptake inhibitor
Causes vasoconstriction and local anesthesia.

Question 14

Clonidine mechanism of action and uses

Answer 14

Sympathoplegic: inhibits postganglionic SNS.
stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system and in decreases in peripheral resistance, renal vascular resistance, heart rate, and blood pressure.
Treats hypertension while increasing renal flow

Question 15

alpha-methyldopa mechanism of action and uses.

Answer 15

Sympathoplegic: inhibits postganglionic SNS.
stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system and in decreases in peripheral resistance, renal vascular resistance, heart rate, and blood pressure.
Treats hypertension while increasing renal flow