Sympatholytic Drugs

Question 1

Examples of non selective alpha receptor blockers

Answer 1

Phenoxybenzamin and phentolamine

Question 2

Which non selective alpha blocker is irreversible

Answer 2

Phenoxybenzamin

Question 3

Clinical application of phenoxybenzamin

Answer 3

Can treat pheochromocytoma

Question 4

What is pheochromocytoma

Answer 4

A tumore which causes release of catecholamines ( norepinephrine and epinephrine)

Question 5

Mechanism of action of phenoxybenzamin

Answer 5

Irreversibly binds to alpha adrenergic receptors to block effects of catecholamines.

Question 6

Effects of non selective alpha blockers

Answer 6

Reduces peripheral resistance
And relaxation of sphincters

Question 7

Non selective alpha antagonist C be used to treat

Answer 7

Hypertension
Urinary retention

Question 8

Side effects of alpha blockers

Answer 8

Hypotension, dizziness vomiting, diarrhea,

Question 9

Examples of selective alpha 1 antagonist

Answer 9

prozasin
Doxazosin
Tamsulosin(urinary retention)

Question 10

Clinical significance of selective alpha 1 blockers

Answer 10

Treat raynaud’s phenomenon
Treat hypertension
Treat urinary retention

Question 11

Adverse effects of selective alpha 1 blockers

Answer 11

Reflex tachycardia
Nasal congestion
Inhibit ejaculation

Question 12

Examples of non selective B blockers

Answer 12

Propranolol
Pindolo
Timolo

Question 13

Examples of selective B1 antagonist

Answer 13

Metoprolo
Acebutolo

Question 14

Examples of beta blockers with intrinsic sympathomimetic activity(partial agonist)

Answer 14

Pindolo, acebutolo, alprenolol oxprenolol

Question 15

Non selective beta antagonist like propranolol, timolo, pindolo are contraindicated in

Answer 15

COPD( emphysema and bronchitis)
Asthma.

Question 16

Timolo can be used to treat?

Answer 16

Open open angle glaucoma( reduce intraocular pressure)