sympathetic pharm

Question 1

presynaptic: inhibits signal propagation

Answer 1

+alpha 2 –>inhibits signal propagation

Question 2

vascular: what causes vasoconstriction & dilation?

Answer 2

+ alpha 1–>vasoCONSTRICTS

+ beta 2 OR + alpha 2–>vasoDILATES

Question 3

respiratory: bronchoDILATION

Answer 3

+beta 2

Question 4

cardiac: increases contractility & conduction

Answer 4

+beta 1 **ONLY FUNCTION!!!

Question 5

hepatic: glycogenolysis

Answer 5

+beta 2

Question 6

pancreatic: increases & decreases insulin release

Answer 6

+beta 2 –>increases

+alpha 2–> DEcreases insulin release

Question 7

iris: mydriasis

Answer 7

+alpha 1

Question 8

ciliary body: decrease or increase aqueous production?

Answer 8

+ beta 2 –>relaxation & INCREASE aqueous production
**- beta 2 OR + alpha 2 –>DECREASES aqueous production
(makes sense BETA BLOCKERS used to treat glaucoma)

Question 9

what does alpha 1 do when stimulated?

Answer 9

1. vascular vasoconstriction
2. mydriasis

receptor activity–> NE»E **only one where norepinephrine dominates!

Question 10

alpha 2 when stimulated?

Answer 10

• *only one to INHIBIT SYMPATHETIC nervous system
  1. inhibit propagation of signal
  2. less insulin released
  3. less aqueous production
  4. vasoDILATION

receptor activity–> E >= NE
epinephrine more potent or equal

Question 11

beta 1 stimulation?

Answer 11

**ONLY FUNCTION: contract & conduction heart

receptor activity–> E=NE EQUAL stimulation

Question 12

beta 2 stimulation?

beta 2 inhibition?

Answer 12

• epinephrin–>more potent
  1. vasoDILATION (in muscles)
  2. bronchoDILATION (airway)
  3. glycogenolysis (more sugar in blood stream)
  4. RELAX & INCREASE aqueous production (paralyze accommodation)

inhibition of beta 2 –>LESS aq. production