Sympathetic Nervous System (SNS) Flashcards
What is a sympathetic nervous system?
A network of nerves that helps your body to activate its { fight and flight } response.
What receptor does the SNS contain?
- Adrenergic receptor
What are the types of Adrenergic receptor ?
- Alpha-1 adrenergic R & Alpha-2 adrenergic R
- Beta-1 adrenergic R, Beta-2 adrenergic R & Beta-3 adrenergic R
Where can you find Alpha-1 adrenergic receptor (AR)?
1- Blood Vessels (Arterioles)
2- Smooth muscle
3- Neck
4- Eye
5- GIT
6- Bladder
What is the effect of Alpha-1 AR?
- Vascular constriction
- Pupil dilation (ciliary muscle constriction)
- Smooth muscle constriction
- Increase BP & BF
- D?
Where can you find Alpha-2 adrenergic receptor (AR)?
1- CNS
2- Pancreas
3- Nerve terminals (prenapsic junction)
What is the effect of Alpha-2 AR?
1- Induce sedation
2- Induce analgesia
3- Induce sympathetic effects
4- Reduce cardiac output
5- Inhibit insulin
Where can you find Beta-1 adrenergic receptor (AR)?
1- Heart
2- Kidney
What is the effect of Beta-1 AR?
1- Increase HB
2- Increase renin secretion
Where can you find Beta-2 adrenergic receptor (AR)?
1- Heart
2- Blood vessels
3- GIT
4- Eye
5- Smooth muscle
6- kidneys
7- Bladder wall
8- Lung
9- Skeletal muscle
10- Uterus ( myometrium)
What is the effect of Beta-2 AR?
- Smooth muscle relaxation
- Increase HB
- Pupil constriction ( ciliary muscle relaxation)
Where can you find Beta-3 adrenergic receptor (AR)?
- Adipose tissue
- Bladder (detrusor muscle)
- Gallbladder
What is the effect of Beta-3 AR?
- Burn fat
- Relaxation of muscle
What are Alpha & Beta receptors?
- Receptors bound by Catecholamines.
What is Catecholamines?
- Hormones produced by the adrenal medulla
