Sympathetic agonists Flashcards
Albuterol
B2 > B1
Bronchodilation
Acute asthma
Salmeterol
B2 > B1
Bronchodilation
Long-term asthma or COPD treatment
Dobutamine
B1 > B2, a
Increases contractility - Rx for heart failure (ionotropic effects are greater than chronotropic)
Cardiac stress testing
Dopamine
D1 = D2, B > a
Heart failure
Shock
Ionotropic and chronotropic effects predominate at high doses
Epinephrine
B > a
Anaphylaxis
Asthma
Open angle glaucoma
Isoproterenol
B1 = B2
Electrophysiological evaluation of tachyarrhythmias
Can worsen ischemia
Norepinephrine
a1 > a2 > B1
1st line for hypovolemic shock and hypotension
Phenylephrine
a1 > a2
Hypotension
Causes mydriasis (dilation) for occular procedures
Rhinitis
Amphetamine
Indirect sympathomimetic
Inhibits the reuptake of norepinephrine
Induces release of stored catecholamines
Cocaine
Indirect sympathomimetic
Inhibits reuptake of norepinephrine
Ephedrine
Indirect sympathomimetic
Induces release of stored catecholamines
Clonidine
Treats hypertensive urgency (does not decrease renal blood flow)
ADHD
Tourette’s
a-methyldopa
Hypertension in pregnancy