Swine Infectious Disease Flashcards
Hemophilus parasuis
• H. parasuis more commonly causes _______, _________ and _______ which leads to _______ in weaned pigs
• _______ clinical signs are uncommon in weaned pigs with Glasser’s disease
Hemophilus parasuis
• H. parasuis more commonly causes polyserositis, polyarthritis and meningitis Glasser’s disease in weaned pigs
• Neurological clinical signs are uncommon in weaned pigs with Glasser’s disease
Fibrinous polyserositis
• In suckling pigs ______ is the most common cause and _____ is a sporadic cause when there is inadequate intake of colostrum.
• In weaned pigs differentials include ______, ______, and _______.
- Although all 3 can cause meningitis in weaned pigs, clinical CNS disease is usually a consistent feature in only ________ infections
Fibrinous polyserositis
• In suckling pigs Strep. suis is the most common cause and E. coli is a sporadic cause when there is inadequate intake of colostrum.
• In weaned pigs differentials include Glasser’s disease, Strep. suis and Mycoplasma hyorhinis.
- Although all 3 can cause meningitis in weaned pigs, clinical CNS disease is usually a consistent feature in only Strep. suis infections
Streptococcus suis
• Common age for disease
• Common lesion, mortality?
• When fibrinous polyserositis predominates, S. suis septicemia is difficult to distinguish from _________
• In general the amount of ____ and the severity of the _______ are greater with Glasser’s disease than with Strep. suis septicemia
• __________ predisposes to S. suis induced septicemic diseases
Streptococcus suis
• Disease is most common in suckling and recently weaned pigs, but can occur in any age
• Fibrinopurulent leptomeningitis causing CNS and high mortality is common
• When fibrinous polyserositis predominates, S. suis septicemia is difficult to distinguish from Glasser’s disease
• In general the amount of fibrin and the severity of the peritonitis are greater with Glasser’s disease than with Strep. suit septicemia
• Acute PRRSV predisposes to S. suis induced septicemic diseases
Erysipelothrix rhusiopathiae • ages • Mortality is highest and lesions most extensive in what age group • common name • Can cause \_\_\_\_\_\_\_ in sows • zoonotic?
Erysipelothrix rhusiopathiae
• E. rhusiopathiae causes disease in all ages
• Mortality is highest and lesions most extensive in
suckling and recently weaned pigs
• Diamond skin disease (thrombosis of cutaneous blood vessels)
• Can cause abortion in sows
• The bacterium has zoonotic potential and may cause endocarditis in humans
Actinobacillus suis
• Causes sporadic outbreaks of ________ in _____ ages of pigs
• In suckling and recently weaned pigs most present as __________
• clinical signs (2)
• Lesions in all ages are the consequence of ______________
Actinobacillus suis
• Causes sporadic outbreaks of fulminant septicemia in all ages of pigs
• In suckling and recently weaned pigs most present as acute death
• clinical signs: fever and multifocal cutaneous hemorrhages
• Lesions in all ages are the consequence of septicemia with
septic embolism
Actinobacillus suis
• Gross Lesions
Actinobacillus suis
• Petechial hemorrhages are diffusely distributed on the serosal surfaces and a wide variety of organs including lungs, kidney, spleen and skin (resembles erysipelas), necrohemorrhagic pneumonia and serofibrinous pericarditis, pleuritis and peritonitis
Arcanobacterium pyogenes
• Commonly is a ________ (2)
• cause what type of infection?
Arcanobacterium pyogenes
• Common isolate from swine, common opportunistic secondary pulmonary pathogen
• localized purulent infection
Porcine dermatitis and nephropathy syndrome (PDNS)
• cause?
• Characteristic lesions include
• Kidney lesion
- What type of hypersensitivity reaction?
Porcine dermatitis and nephropathy syndrome (PDNS)
• Precise cause is unknown
• Characteristic lesions include large hemorrhagic cutaneous infarcts mainly located on the perineal area and hind limbs
• Kidney - necrotizing and fibrinous glomerulonephrtitis and systemic necrotizing vasculitis (with thrombosis)
- type III
Porcine reproductive and respiratory syndrome virus (PRRSV)
- gross lesions (2)
- PRRSV causes what that can lead to and increased susceptibility to what infections?
- lungs (consolidation) and lymph node enlargement
- decreased phagocytic activity of pulmonary intravascular macrophages –> increased susceptibility to Strep. suit and S. choleraesuis infections
Post weaning Multisystemic Wasting Syndrome (PMWS)
- associated with what virus?
- characteristic lesion
- diagnosis requires what 3 things?
- virus concentration is highest in the ____
- porcine circovirus 2 (PCV2)
- granulomatous lymphadenitis (any internal organ) +/- globular intracytoplasmic viral inclusion bodies
- clinical wasting, histological lesions, and PCV2 in lesions
- heart
Ddx pig diarrhea without blood (7)
- colibacillosis
- clostridium perfringens type A
- coccidiosis
- viral enteritis
- proliferative enteritis
- whipworms
- intestinal spirochetosis
Ddx pig diarrhea with blood (5)
- clostridium perfringens type A
- salmonellosis
- hemorrhagic enteritis
- swine dysentery
- whipworms
Colibacillosis
- EPEC:
- age
- MOA
- attaching and effacing E. coli
- 1-6 wks
- colonize and cause degeneration of villous enterocytes
Colibacillosis
- ETEC:
- age
- MOA
- hemolytic or non-hemolytic, small intestine only
- suckling and weaned pigs
- colonize brush border
Edema disease
- ETEC secretes _____ which leads to _______
- gross lesions:
-
- shiga-like toxin II –> fluid loss and edema
- brain stem lesions, palpebral edema, edema of the gastric and ball bladder mucosa, mesentery, and mesocolon
Clostridium perfringens Type C
- age
- common place for lesions
- 3 common lesions
- 1-4 days
- small intestine
- bloody diarrhea, necrohemorrhagic enteritis, subserosal emphysema
Clostridium perfringens Type A
- age
- morbidity/mortality?
- lesion
- 1-4 days
- high morbidity, low mortality
- mesocolon edema
Clostridium difficile
- age
- clinical signs
- lesions
- 1-14 days
- ascites, subcutaneous edema
- diffuse mesocolonic edema, erosive colitis, fibrinosuppurative exudation
Salmonella choleraesuis
- age
- phagocytosed by _________
- colonize:
- acute form causes:
- chronic form causes:
- weaner and growing pigs
- M cells in Payers patches
- SI, colon, mesenteric LN, Gall bladder
- fibrinonecrotic ileocolitis
- necrosis/ulceration of cecum and colon: button ulcers
Coccidiosis • organism • age • lesion • Diagnosis
Coccidiosis
• Isospora suis : obligate intracellular pathogen
• 5-7 days of age
• Fibrinonecrotic pseudomembranous enteritis (no hemorrhages)
• Oocysts: demonstrable in feces
