Swe chem 02 - Protein Flashcards
Amino acid formula
H. R. O..
N. C. C.
H. H. OH.
Amount of amino acids
20
What amino acid isn’t an optical isomer
Glycine
Optical isomer
Chiral
Essential amino acids
9 st
Valine, leucine, lysine
R groups can be…
Non-polar
polar
neg. Charged
Pos. Charged
Peptide bonds
H from the amino group, OH from the carboxyl group => HOH
Zwitterion
Amino group is ionic, carboxyl group is ionic. Molecule is neutral
Primary structure
Order of amino acids
Secondary structure
Folds
Alfa helix or beta pleated
Alpha helix
Tends to have small R groups
Hydrogen bonds
Beta pleated
Tends to have larger R groups
Hydrogen bonds
Tertiary structure
3D shape - Interaction of R groups
Hydrophobic inwards
Hydrophilic outwards
Forces determining the tertiary structure
Electrostatic charges
Hydrogen bonds
Disulfic bonds (smells bad)
Quaternary structure
Several chains making up one protein
Can include non- protein groups such as iron in hemoglobin (4 strands)