Swe Chem 02 - Nucleic Acid Flashcards
Nucleic acid
RNA and DNA
Made up of nucleotides
Nucleic acid
Phosphorus group +
Sugar +
Nitrogenous base
RNA sugar
Ribose (5C)
DNA sugar
Deoxyribose (5C)
RNA bases
A. U
C. G
DNA bases
A. T
C. G
DNA
Double stranded nucleic acid
RNA
Single stranded nucleic acid
Central Dogma of Biochemistry
DNA => RNA => Protein
Ribosome A
Aminoacyl
Ribosome P
Peptidyl
Ribosome E
Exit
Splicing
Introns are removed with spliceosomes
Resulting in ligated exons
Introns
Unnecessary genetic info on primary mRNA strand
Exons
The wanted parts of the primary mRNA strand that makes up the nature mRNA strand
Primary mRNA strand
Initially copied sequence from the DNA strand
Mature mRNA strand
Spliced mRNA sequence that gets translated into protein by the ribosome
2 types of ribosome
Free-floating in cytosol
Attached to the rough ER (for protein exiting the cell)
Stabilisera of mRNA
5’ G-cap (5’-5’ through triphosphate)
Poly-A tail (3’ end)
Promoter
Up strand “heads up” TATA box
Helicase
Unwinds
Gyrase
Relieves mention in the helicase
Anti codon
On tRNA to match with the codon in mRNA