Suspensions

Question 1

Common pharmaceutical products that are suspensions include:

Answer 1

Ear drops
Enemas 
Inhalations
Lotions
Mixtures for oral use

Question 2

Oral suspensions are

Answer 2

Oral liquids containing one or more active ingredients suspended in a suitable vehicle

Question 3

Suspended solids may slowly separate on standing

Answer 3

But are easily redispersed

Question 4

Pharmaceutical Suspension

Answer 4

A preparation where we least one of the active ingredients is suspended throughout the vehicle.

Question 5

Why do suspensions require shaking before a dose is administered?

Answer 5

In a suspension at least of the ingredients is not dissolved in the vehicle

Question 6

Diffusible Suspensions

Answer 6

Suspensions containing light powders which are insoluble or only very slightly soluble in the vehicle.

Question 7

For diffusible suspensions shaking allows powders to

Answer 7

Disperse evenly throughout the vehicle for long enough to allow an accurate dose to be poured.

Question 8

Advantages of suspensions as dosage forms 1.

Answer 8

Insoluble drugs may be more palatable
Insolube drugs may be more stable
Suspended insoluble powders are easy to swallow

Question 9

Advantages of suspensions as dosage forms 2.

Answer 9

The suspension format enables easy administration of bulk insoluble powders
Absorption will be quicker than solid dosage forms
Lotions will leave a cooling layer of medicament on the skin
It is theoretically possible to formulate sustained-release preparations

Question 10

Disadvantages of suspensions as dosage forms

Answer 10

Preparation requires shaking before use.
Accuracy of the dose is likely to be less than with an equivalent solution
Storage conditions can affect disperse system
Suspensions are bulky, difficult to transport + prone to container breakages

Question 11

Indiffusable suspensions

Answer 11

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