surgical site infection prevention Flashcards

1
Q

classification of SSIs

A

superficial: skin and subQ tissue
deep: Deep soft tissue (fascia and muscle)
organ/space: organ/space

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2
Q

prehospital interventions

A

smoking cessation, MRSA screening and decolonization, bowel prep

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3
Q

smoking and SSIs

A

smokers have the highest risk for SSIs
smoking results in: vasoconstriction of vessels in the surgical bed, tissue hypovolemia and hypoxia, decreased transportation of nutrients, altered immune response
smoking cessation: includes tobacco, marijuana and e-cigarettes, must stop completely for a minimum of 4-6 weeks before surgery, decreases surgical site infections and other complications, nictotine replacement therapy is endorsed

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4
Q

MRSA screening and decolonization

A

recommended for: total joint replacement and cardiac procedures**
screen for MRSA and IF positive**:
-decolonization - no standard protocol (i.e. mupirocin and chlorhexidine)
-must be completed close to the day of surgery
-compliance is key

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5
Q

bowel preparation

A

recommended for: elective colorectal surgeries
lowers rates of : SSIs, anastomotic leaks, C. diff and post op illues, LOS and readmission rates
combination* of mechanical bowel prep plus* neomycin 1 g + metronidazole 1 g PO at 1 pm, 2 pm and 10 pm the day before surgery; if allergic to metronidazole use erythromycin 1 g + neomycin 1 g at the above times
must be completed day before surgery**
compliance is key: must use both** otherwise no benefit

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6
Q

glucose control

A

short term perioperative glucose control with insulin:

  • all surgical patients regardless of diabetic status
  • lowers risk for SSIs
  • cardiac patient goal under 180
  • all other patients 110-150
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7
Q

patients who benefit from antibiotic prophylaxis

A

procedures with a high rate of infection
procedures with a low incidence but severe consequences if an infection occurs
balance cost of treating and morbidity of an infection vs cost and morbidity of using prophylaxis

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8
Q

antimicrobial selection overview

A

base on antimicrobial stewardship policies**
active against most likely pathogens
use most narrow spectrum agent
maintains adequate serum and tissue concentrations during the procedure
safe
administered for the shortest period of time

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9
Q

when to use cefazolin for surgical prophylaxis

A

billiary tract, cardiac, gastroduodenal, head and heck (w placement of prosthesis), neurosurgery, OB-GYN, ortho, small intestine (non-obstructed), thoracic, urologic, vascular

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10
Q

when to use cefazolin + metronidazole for surgical prophylaxis**

A

appendectomy, colorectal, head and neck (cancer surgery), small intestine (obstructed)

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11
Q

when to use vancomycin for surgical prophylaxis

A

B-lactam allergy AND

cardia, neuro, ortho, thoracic, vascular

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12
Q

when to use clindamycin + gentamicin for surgical prophylaxis

A

B-lactam allergy AND

appendectomy, billiary tract, colorectal, gastroduodenal, OBGYN, small intestine

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13
Q

when to use vancomycin + getnamicin for surgical prophylaxis

A

B lactam allergy AND gastroduodenal PEG placement or revistion

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14
Q

when to use clindamycin for surgical prophylaxis

A

B-lactam allergy AND

head and neck

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15
Q

when to use metronidazole + gentamicin for surgical prophylaxis

A
B-lactam allergy AND
small intestine (obstructed)
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16
Q

when to use ciprofloxacin for surgical prophylaxis

A

B-lactam allergy and urologic

17
Q

penicillin allergy

A

assess patients allergy history
patients with documented or presumed IgE-mediated pen allergic reactions (anaphylaxis, urticaria or hives, bronchospasm, exfollative dermatitis (SJS, toxic epidermal necrolysis)) - cephalosporins should not be used
Cephalosporins can safely be used in patients with an allergic reaction to penicillins that is not IgE-mediated

18
Q

role of vanc

A

no role for routine use of vanc in patients not colonized with MRSA
less effective than cefazolin for preventing SSIs caused by MSSA

19
Q

cefazolin dose

A

current guidelines: 2 g dose and 3 g for patients 120+ kg

20
Q

anitbiotics dosing in surgical prophylaxis

A

completely infused within 60 minutes prior to surgical incision to optimize adequate drug tissue levels at the time of initial incision
vanc or a FQ should be within 120 minutes before surgical incision due to their prolonged infusion times

21
Q

repeat dosing

A

repeat dosing is warranted for procedures that exceed 2 half-lives of the drug and for procedures in which there is excessive blood loss (over 1500 mL_
dosing interval should be measured based from the time of the preoperative dose

22
Q

cefazolin redosing interval

A

4 hours

23
Q

clindamycin redosing interval

A

6 hours

24
Q

duration

A

antibiotics should be discontinues at the end of incision closure, this is usually 1 dose