Surgical Oncology Flashcards
What are the steps of Getting treated for Ca?
Diagnosis and staging: obtain tissue, stage, monitor for response to therapy
Fine needle aspiration: done in office, takes cells and needs to be read by cytopathologist.
Core Needle biopsy: needle takes a core of tissue out, can look at architecture, more infvasive, more tissue info
Incisional/Excisional biopsy: when previous ones dont work, take out part or the whole mass. may make sx more challenging
Remove needle track in sx
What are the diff ways to do sx?
Primary tumor resection: Take out tumor and normal tissue around the tumor. margin.
Resection of regional lymph nodes: most prevelent for solid tumors, important in prognosis, prevents recurrence, imp for predicting who does well and not
Resection of Metastatic Dz: survival is good if we go after the metastatic implant. based on disease process and health of the pnt.
Tumor debulking; removing as much as is feasible. and ppl do better.
How do you use surgery to prevent cancer?
Angelina Jolie.
BRCA 1/2
Undescended testicle has higher risk for ca - pull it down
Genetic problems linked with cancers can be treated with sx (colectomy, thyroidectomy, mastectomy, etc.)
What is the palliative role of Sx in cancer?
Improvement of QOL
remember that sx is a trauma and last thing we want is to kill them.
common: pain, obstruction, vascular access, feeding tube, pain, bleeding, wounds
patients have an ASA class
rated based on health, comorbidities, etc. the bigger the number, the worse off the patient is and will likely do worse with sx
Patient selection
ECOG - classification system
Karnofsky - classification system
0 on ecog is 100% on K. fully active, no complaints.
5 on ecog is 0% on K , bad
DO all ca need to be treated with sx?
NO. some are better with chemo/radiation
What are the major challenges associated with this?
Accurate identification of pnts who can be cured
Selection of local treatments that provide balance between local cure and impact of adjuvant treatements on survival and QOL
want to find it early.
get screened. mutations accumulate.
what are the risk factors of Colon cancer?
Age, hi fat diet, polyps, hx, famhx, IBD,
Symptoms: change in bowel habits, bleeding,