Surgical Management of CAD (Powerpoint1) Flashcards

1
Q

Why is the Left Main artery not grafted directly?

A

It is inaccessible without dividing the pulmonary artery and the aorta.

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2
Q

Which artery supplies 50% of the blood flow to the left ventricle?

A

The LAD (Left anterior descending.)

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3
Q

Which artery supplies blood flow to the left atrium?

A

The circumflex (Cx)

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4
Q

The ramus supplies blood flow to which area of the heart?

A

The LV (but this artery is not present in everyone.)

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5
Q

What is the reason for inducing hypothermia during cardioplegia?

A

Hypothermia reduces myocardial oxygen demand.

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6
Q

During CPB, where is the arterial cannula placed?

A

Into the aorta.

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7
Q

During CBP, hwere is the venous cannula placed?

A

Into the RA.

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8
Q

Why is aortic sclerosis a contraindication for CABG?

A

Aortic sclerosis prevents safe cross clamping of the aorta and has increased risk of stroke.

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9
Q

Activation of mast cells during CBP, causes histamine release. What is the effect on the vascular system?

A
  • Capillaries become leaky
  • Smooth Muscle contracts
  • Vasodilation
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10
Q

Why do platelets lower after CBP?

A

Platelets adhere to the synthetic substances of the pump.

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11
Q

Why are platelets less effective after CBP?

A

Hypothermia causes platelet dysfunction.

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12
Q

What effect does the CBP have on red blood cells?

A

The suction of the machine can cause hemolysis.

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13
Q

Which catecholemines are increased during CBP?

A
  • Epinephrine (10x increase in production
  • Norephinephrine (4x increase in production)
  • Vasopression (20x increase in production)
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14
Q

What happens to cortisole production during CBP?

A

Cortisol production increases (Raising serum blood sugar.)

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15
Q

Why is there less insulin after/during CBP?

A

Hypothermia of the pancreas impairs insulin production.

Also, insulin binds to the oxygenator tubing.

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16
Q

Activation of what system during CBP causes increased vasopressin production (ADH)?

A

R-A-A-S Renin-Angiotension-Aldosterone System

17
Q

What happens to sodium? To potassium? During CBP

A

Sodium retention is promoted

Potassium is excreted

18
Q

How fast does ECF (Extracellular fluid) build up during CBP?

A

800 mL/hour of bypass.

19
Q

Protamine reaction will manifest in what symptoms?

A

Low SVR, flushing, hypotension

20
Q

Why is the IMA the first choice for conduits?

A

It has 90% patency at 10 years after surgery.

21
Q

The radial artery is the second choice for conduit but has what complication?

A

Vasospasm - treat with nitrates or calcium channel blockers after surgery

22
Q

Normal CVP

A

2-6

23
Q

Normal PAOP

A

6-12