Heart Failure and Valvular Diseases (5) Flashcards

1
Q

CO =

A

HR x SV

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2
Q

SV =

A

Preload, afterload and contractility

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3
Q

What do ejection fraction and cardiac output attempt to measure?

A

Contractility - but contractility is always affected by loading conditions.

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4
Q

LV hypertrophy is common in people with which conditions?

A

Hypertension, aortic stenosis

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5
Q

In patients with LV hypertrophy, which is more appropriate, inotropes or volume?

A

VOLUME - a stiff ventricle requires higher filling pressures to function. Vasodilators are a second choice if pt is euvolemic. Inotropes are the last choice.

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6
Q

What are the four risk factors associated with developing ***HF?

A

Smoking, Obesity, Diabetes, hypertension

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7
Q

***For best performance, patients with systolic CHF need ____ _____ for optimal contractility.

A

Volume loading.

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8
Q

***How can one improve contractility in a patient with sCHF?

A

Volume loading, lower BP and CO, IABP, inotropes

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9
Q

An elevated BNP is a diagnostic indicator of what?

A

Diastolic CHF

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10
Q

Myocardial edema causes universal ______ _______ in the first 3 hours after surgery.

A

diastolic dysfunction (heart muscle can’t relax/ventricle can’t fill.)

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11
Q

***How can one treat the diastolic dysfunction after cardiac surgery?

A
Give volume (increase preload)
Lower HR (increase filling time)
Prolong AV delay (if pacing is required)
Diuresis and volume expansion
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12
Q

***hypoxemia, hypercarbia, and acidosis all (Increase/Decrease) pulmonary pressures.

A

INCREASE - causing R heart strain.

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13
Q

***What is a ventilator strategy to reduce pulmonary pressures?

A

hyperventilate - lowering CO2 and causing alkalosis.

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14
Q

Cardiopulmonary bypass causes SIRS, which leads to an (increased/decreased) PVR

A

Cardiopulmonary bypass causes SIRS, which leads to an increased PVR

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15
Q

pulmonary hypertension is associated with? (2 causes)

A

Left sided valvular disease (mitral stenosis/regurg) or diseases of hypoxia (ex, OSA)

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16
Q

difference between nitroglycerin and nitroprusside?

A

Nitroglycerin –> Lowers CO

NitropruSSide –> lowers SVR

17
Q

What are the benefits of inhaled nitrous oxide?

A

selective, increases PaO2, decreases PVR, and increases CO

18
Q

prostaglandins/prostacylcin analogs have what effect on the pulmonary vasculature?

A

pulmonary vasodilators

19
Q

inotropes are not helpful in patients with which heart disease?**

A

diastolic dysfunction*****

20
Q

Patients with Aortic stenosis are at high risk for?

A

Myocardial ischemia

21
Q

Which dysarthria is common after mitral valve surgery?

A

A fib (new or recurrent)

22
Q

Most common cause of mitral regurgitation?

A

Myxomatous degeneration

23
Q

What conditions worsen MR?

A

LV dilation, increased SVR, aortic stenosis

24
Q

Mitral valve: repair vs replace?

A

Bioprosthetic valves deteriorate, but allow native heart function to be preserved (EF)

Long term AC required with mechanical valves

25
Q

What happens to after load after mitral valve repair?

A

It is increased (blood not being regurgitated into LA). Now patient may have low CO. the incompetent valve was providing compensatory mechanism.

Compliant, poorly contracting ventricle. (LV Systolic dysfunction)

26
Q

SAM

A

SYstolic anterior motion of the mitral valve

27
Q

Leaflets of the mitral valve cause a Left Ventricular Outflow Tract (LVOT) obstruction

A

SAM physiology (systolic anterior motion of mitral valve)

28
Q

What exacerbates Sam physiology?

A

Reduced LV preload
Increased catecholemines
Inotropes
Decreased after load

29
Q

What is the treatment for SAM?

A

Stable HR AND Rhythm
Maximize filling time
Volume, vasopressors