Surgery - Urology Flashcards
What is the best form of imaging for kidney stones?
CT KUB
Recall the 4 main types of kidney stone in order of highest to lowest radiointensity
Calcium phosphate
Calcium oxalate
Triple (struvite) stones
Uric acid (radiolucent)
Which type of kidney stone is associated with urease bacteria?
Triple (struvate) stones
Which type of kidney stone is associated with hypercalciuria?
Calcium oxalate
How should kidney stone pain be managed?
PR/IM diclofenac
Recall one contra-indication to diclofenac
CVS disease
How should kidney stones be managed depending on size?
Renal stones
Watchful waiting if < 5mm +/- tamsulosin (up to 1cm)
5-10mm shockwave lithotripsy
10-20 mm shockwave lithotripsy OR ureteroscopy
<2cm and pregnant: uteroscopy
> 20 mm percutaneous nephrolithotomy
Uretic stones
< 10mm shockwave lithotripsy +/- alpha blockers
10-20 mm ureteroscopy
If hydronephrosis/infection: percutaneous nephrostomy and antibiotics
Recall 2 options for medically managing BPH and some side effects of each
- alpha-1 antagonists (tamsulosin): postural hypotension, dry mouth
- 5 alpha reductase inhibitors (finasteride): ED, reduced libido, gynaecomastia, ejaculation problems
What is the main way in which BPH can be surgically managed?
TURP (transurethral resection of the prostate)
What is the main complication of TURP to be aware of?
TURP syndrome
Hyponatraemia, fluid overload and glycine toxicity caused by over-irrigation
When can PSA levels not be done?
Within:
- 6 weeks of a prostate biopsy
- 1 week of DRE
- 4w following a proven UTI/prostatitis
- 48 hours of vigorous exercise and/or ejaculation
When would a multi-parametric MRI be used to investigate possible prostate cancer?
If PSA is inappropriate or if high chance of Ca
What is the gold-standard investigation for prostate cancer?
Multiparametric MRI (this has replaced TRUS-guided biopsy)
Recall 3 options for managing localised prostate cancer (T1/T2)
- Conservative with active monitoring
- Radical prostatectomy
- Radiotherapy (external beam and brachytherapy)
Recall 3 options for managing localised advaced prostate Ca
- Hormonal therapy
- Radical prostatectomy
- Radiotherapy
How should metastatic prostate cancer disease be managed?
Hormonal therapy only
What are the options for hormone therapy in prostate cancer?
Synthetic GnRH agonist + 3w cover of anti-androgen
Recall 2 types of benign epithelial renal tumour
Papillary adenoma
Renal oncocytoma
What sort of tumour is an angiomyolipoma?
Benign mesenchymal renal tumour composed of thick-walled blood vessels, smooth muscle and fat
What is the maximum size for a papillary adenoma?
15mm
If more than this = malignant papillary renal cell carcinoma
What type of renal tumour can be seen in Birt-Hogg-Dube syndrome?
Renal oncocytoma
What type of renal tumour can be seen in tuberous sclerosis?
Angiomyolipoma
Which genetic syndrome predisposes to renal cell carcinoma?
Von Hippel Lindau
What are the 3 main subtypes of renal cell carcinoma, and which is most common
Clear cell (70%)
Papillary
Chromophobe
Which tumours are people with Von-Hippel-Lindau predisposed to?
Phaeochromocytoma
Neuroendocrine pancreatic
Clear cell renal
Which type of renal cell tumour is associated with loss of 3p?
Clear cell renal
Which type of renal tumour is associated with long-term dialysis?
Papillary renal cell carcinoma
What is Wilm’s tumour?
Nephroblastoma
How should high-grade transitional cell carcinomas be managed?
1st: intravesical immunotherapy
2nd: radical cystectomy
How should traumatic urethral injuries be investigated and managed?
Ix: ascending urethrogram
Mx: suprapubic catheter
How should traumatic bladder injuries be investigated and managed?
Ix: Intravenous urogram or cystogram
Mx: laparotomy if intraperitoneal, conservative if extraperitoneal
What proportion of testicular tumours are germ cell tumours?
95%
What are the subtypes of germ cell testicular tumours?
Seminomas (50%)
Non-seminoma (embryonal, yolk sac, teratoma an choriocarcinoma)
What is the biggest risk factor for testicular seminoma?
Cryptochidism
What are the signs and symptoms of testicular cancer?
Painless lump +/- hydrocele, gynaecomastia
How should testicular cancer be investigated?
1st = USS
2nd = AFP, hCG, LDH
3rd = CT TAP
NO biopsy
How can testicular cancer be managed?
Orchidectomy +/- chemotherapy +/- radiotherapy
Is the cremasteric reflex pos or neg in testicular torsion?
Neg
What is the cremasteric reflex?
Stroking of the skin of the inner thigh causes the cremaster muscle to contract and pull up the ipsilateral testicle toward the inguinal canal
What is Prehn’s test?
Elevating scrotum and assessing for difference of pain - positive if pain is relieved
Is Prehn’s test pos or neg in testicular torsion?
Neg
What condition is Prehn’s test positive in?
Epididymitis
How should testicular torsion be managed?
Surgical exploration + BL orchidopexy
What is an orchidopexy
Surgical procedure that moves undescended testicle into the scrotum, permanently fixing it there
What are the main RFs for ED?
EtOH
Drugs (beta-blockers, SSRI)
CVD RFs (metabolic syndrome, hyperlipidaemia etc)
How should ED be investigated?
QRisk score Free testosterone (9-11am) --> if low, FSH, LH, prolactin --> if abnormal, refer to endo