Surgery/Peri-Operative Care

Question 1

Which microorganisms are the most common cause of surgical site infection following a clean procedure?

Answer 1

S. aureus

S. pyogenes (group A Beta haem step)

Question 2

Which is a good first choice for antibiotic in a wound infection scenario?

Answer 2

IV Flucloxacillin

-has activity against step and methicillin sensitive S. aureus

Question 3

Which antibiotic predisposes to C Diff and causes Cholestatic jaundice as a side effect?

Answer 3

Co-Amoxiclav

Question 4

Which drug should be prescribed if the causative agent is confirmed as meticillin sensitive S aureus?

Answer 4

Flucloxacillin

-change to clindamycin/clarithromycin if penicillin allergic

Question 5

Which drug should be prescribed if the causative agent is S. pyogenes?

Answer 5

Benzylpenicillin

-change to clindamycin/clarithromycin if penicillin allergic

Question 6

Which drug should be prescribed if the causative agent is MRSA?

Answer 6

Vancomycin

-oral switch to clarithromycin

Question 7

Which bacteria is most often responsible for late onset valve endorcarditis?

Answer 7

Coagulase negative staphylococcus

Question 8

What properties do coagulase negative staphs have which makes them likely to cause valve infection?

Answer 8

Produce slime layer which mediates adhesion