Surgery Flashcards
0
Q
What two antiseptics are used to prepare the patient?
A
Iodine
Chlorhexidine
1
Q
What are the four hand scrub washes?
A
Chlorhexidine
Iodine
Alcohol
Sterillium
2
Q
What are Halsteds principles? (7)
A
Surgical asepsis Gentle tissue handling Accurate haemostasis Preservation of vascularity Careful approximation of tissue Obliteration of dead space No tissue tension
3
Q
What are the six stages of wound healing?
A
Acute inflammatory Parenchymal regeneration Re-epithelialisation and cell migration Proliferation of parenchyma and stromal cells Synthesis of ECM Remodelling
4
Q
What cells are involved in coagulation?
A
Platelets
5
Q
What cells are involved in inflammation? (3)
A
Platelets
Macrophages
Neutrophils
6
Q
What cells are involved in migration/proliferation? Angiogenesis Epithelium Fibroplasia Contraction
A
Macrophages Lymphocytes Fibroblasts Epithelial cells Endothelial cells
7
Q
What cells are involved in remodelling?
A
Fibroblasts
8
Q
Describe the initiation coagulation phase of wound healing?
A
Death of epi/dermal cells Damage to collagenous fibres Small vessel rupture Release of blood into wound Platelet deposition and aggregation Release of cytokines and GF PDGF, TGFb and fibronectin ➡️ fibrin clot
9
Q
Describe the initiation of the inflammatory phase of wound healing?
A
Damage attracts and activated infiltrating cells - leucocytes
(Neutro, mono, macro, lympho)
Macrophages remove debris, recruit/activate GF, chemokines, cytokines - phagocytosis, angiogenesis, matrix synthesis regulation
