Surfactants Flashcards

0
Q

alkali metal and ammonium soaps - emulsion type

A

O/W

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1
Q

Alkali metal and ammonium soaps - surfactant type

A

anionic

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2
Q

alkali metal and ammonium soaps - pH stability

A

sensitive to acids

stable > pH 10

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3
Q

alkali metal and ammonium soaps - cations/anions/electrolytes stability

A

Al3+, Ca2+, Mg2+ or Zn 2+ cause phase reversal

electrolytes salt out the soap

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4
Q

alkali metal and ammonium soaps - Route of administration

A

not for oral (unpleasant taste) and not on broken skin (alkaline pH)

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5
Q

alkali metal and ammonium soaps - miscellaneous

A

resistant to attack by microorganisms

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6
Q

alkali metal and ammonium soaps - In situ?

A

Yes

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7
Q

Soaps of divalent and trivalent metals - surfactant type

A

anionic

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8
Q

Soaps of divalent and trivalent metals - emulsion type

A

W/O

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9
Q

Soaps of divalent and trivalent metals - examples

A

calcium oleate

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10
Q

Soaps of divalent and trivalent metals - pH sensitivity

A

less sensitive to acids

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11
Q

Soaps of divalent and trivalent metals - cations/anions/electrolytes

A

-

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12
Q

Soaps of divalent and trivalent metals - Route of Administration

A

Not for Oral

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13
Q

Soaps of divalent and trivalent metals - miscellaneous

A

they are less alkaline

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14
Q

Soaps of divalent and trivalent metals - in situ?

A

Yes (fatty acid with lime water)

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15
Q

Amine Soaps - surfactant type

A

anionic

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16
Q

Amine Soaps - Emulsion type

A

O/W

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17
Q

Amine Soap - Examples

A

triethanolamine stearate

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18
Q

Amine Soaps - pH

A

sensitive to acids

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19
Q

Amine Soaps - cations/anions/electrolytes

A

resistance to polyvalent cations

sensitive to high concentration of electrolytes

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20
Q

Amine Soaps - Route of administration

A

not for oral

can be applied to the skin

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21
Q

Amine Soaps - miscellaneous

A

for neutral (7.5-8) O/W emulsions

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22
Q

Amine Soaps - In Situ?

A

Yes

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23
Q

Sulfated and sulfonated compounds - Surfactant type

A

anionic

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24
Sulfated and sulfonated compounds - emulsion type
O/W
25
Sulfated and sulfonated compounds - examples
esters of fatty alcohols and sulphuric acids | sodium lauryl sulfate (SLS/SDS)
26
Sulfated and sulfonated compounds - pH
-
27
Sulfated and sulfonated compounds - cations/anions/electrolytes
cationic emulsifying agents such as cetrimide and cationic medicaments
28
Sulfated and sulfonated compounds - route of administration
-
29
Sulfated and sulfonated compounds - miscellaneous
high water solubility | in conjunction with fatty alcohols produce stable emulsions
30
Sulfated and sulfonated compounds - In situ?
-
31
Quaternary Ammonium Compounds - Surfactant type
cationic
32
Quaternary Ammonium Compounds - Emulsion type
O/W
33
Quaternary Ammonium Compounds - Examples
Cetrimide
34
Quaternary Ammonium Compounds - pH stability
stable at pH 3-7
35
Quaternary Ammonium Compounds - cations/anions/electrolytes
incompatible with anionic surfactants and polyvalent anions
36
Quaternary Ammonium Compounds - routes of administration
good for skin application
37
Quaternary Ammonium Compounds - miscellaneous
``` poor emulgents (need fatty alcohols) has antimicrobial activity ```
38
Quaternary Ammonium Compounds - in situ?
-
39
Glycol and Glycerol - Surfactant Type
non-ionic
40
Glycol and Glycerol - Emulsion Type
W/O
41
Glycol and Glycerol - Examples
glycol and glycerol esters of certain higher fatty acids | glycerol monostearate
42
Glycol and Glycerol - pH
-
43
Glycol and Glycerol - cations/anions/electrolytes
-
44
Glycol and Glycerol - route of administration
-
45
Glycol and Glycerol - Miscellaneous
strongly hydrophobic nature poor (W/O) emulsions mix with little soap (SLS) to get good emulsions
46
Glycol and Glycerol -In situ?
-
47
Sorbitan Esters - Surfactant Type
Non-ionic
48
Sorbitan Esters - Emulsion Type
W/O
49
Sorbitan Esters - Examples
Spans
50
Sorbitan Esters - pH
-
51
Sorbitan Esters - cations/anions/electrolytes
-
52
Sorbitan Esters - route of administration
-
53
Sorbitan Esters - Miscellaneous
-
54
Sorbitan Esters - in situ?
-
55
Polyethylene glycol derivatives of sorbitan esters - surfactant type
non-ionic
56
Polyethylene glycol derivatives of sorbitan esters - emulsion type
O/W
57
Polyethylene glycol derivatives of sorbitan esters - Examples
Tweens
58
Polyethylene glycol derivatives of sorbitan esters - pH
-
59
Polyethylene glycol derivatives of sorbitan esters - cations/anions/electrolytes
-
60
Polyethylene glycol derivatives of sorbitan esters - route of administration
-
61
Polyethylene glycol derivatives of sorbitan esters - miscellaneous
-
62
Polyethylene glycol derivatives of sorbitan esters - in situ?
-
63
Alkali metal and ammonium soaps - examples
salt of long chain fatty acids | sodium stearate