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Pharmacy > Surfactants > Flashcards

Surfactants Flashcards

0
Q

alkali metal and ammonium soaps - emulsion type

A

O/W

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1
Q

Alkali metal and ammonium soaps - surfactant type

A

anionic

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2
Q

alkali metal and ammonium soaps - pH stability

A

sensitive to acids

stable > pH 10

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3
Q

alkali metal and ammonium soaps - cations/anions/electrolytes stability

A

Al3+, Ca2+, Mg2+ or Zn 2+ cause phase reversal

electrolytes salt out the soap

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4
Q

alkali metal and ammonium soaps - Route of administration

A

not for oral (unpleasant taste) and not on broken skin (alkaline pH)

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5
Q

alkali metal and ammonium soaps - miscellaneous

A

resistant to attack by microorganisms

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6
Q

alkali metal and ammonium soaps - In situ?

A

Yes

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7
Q

Soaps of divalent and trivalent metals - surfactant type

A

anionic

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8
Q

Soaps of divalent and trivalent metals - emulsion type

A

W/O

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9
Q

Soaps of divalent and trivalent metals - examples

A

calcium oleate

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10
Q

Soaps of divalent and trivalent metals - pH sensitivity

A

less sensitive to acids

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11
Q

Soaps of divalent and trivalent metals - cations/anions/electrolytes

A

-

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12
Q

Soaps of divalent and trivalent metals - Route of Administration

A

Not for Oral

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13
Q

Soaps of divalent and trivalent metals - miscellaneous

A

they are less alkaline

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14
Q

Soaps of divalent and trivalent metals - in situ?

A

Yes (fatty acid with lime water)

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15
Q

Amine Soaps - surfactant type

A

anionic

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16
Q

Amine Soaps - Emulsion type

A

O/W

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17
Q

Amine Soap - Examples

A

triethanolamine stearate

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18
Q

Amine Soaps - pH

A

sensitive to acids

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19
Q

Amine Soaps - cations/anions/electrolytes

A

resistance to polyvalent cations

sensitive to high concentration of electrolytes

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20
Q

Amine Soaps - Route of administration

A

not for oral

can be applied to the skin

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21
Q

Amine Soaps - miscellaneous

A

for neutral (7.5-8) O/W emulsions

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22
Q

Amine Soaps - In Situ?

A

Yes

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23
Q

Sulfated and sulfonated compounds - Surfactant type

A

anionic

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24
Q

Sulfated and sulfonated compounds - emulsion type

A

O/W

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25
Q

Sulfated and sulfonated compounds - examples

A

esters of fatty alcohols and sulphuric acids

sodium lauryl sulfate (SLS/SDS)

26
Q

Sulfated and sulfonated compounds - pH

A

-

27
Q

Sulfated and sulfonated compounds - cations/anions/electrolytes

A

cationic emulsifying agents such as cetrimide and cationic medicaments

28
Q

Sulfated and sulfonated compounds - route of administration

A

-

29
Q

Sulfated and sulfonated compounds - miscellaneous

A

high water solubility

in conjunction with fatty alcohols produce stable emulsions

30
Q

Sulfated and sulfonated compounds - In situ?

A

-

31
Q

Quaternary Ammonium Compounds - Surfactant type

A

cationic

32
Q

Quaternary Ammonium Compounds - Emulsion type

A

O/W

33
Q

Quaternary Ammonium Compounds - Examples

A

Cetrimide

34
Q

Quaternary Ammonium Compounds - pH stability

A

stable at pH 3-7

35
Q

Quaternary Ammonium Compounds - cations/anions/electrolytes

A

incompatible with anionic surfactants and polyvalent anions

36
Q

Quaternary Ammonium Compounds - routes of administration

A

good for skin application

37
Q

Quaternary Ammonium Compounds - miscellaneous

A 
poor emulgents (need fatty alcohols) 
has antimicrobial activity
38
Q

Quaternary Ammonium Compounds - in situ?

A

-

39
Q

Glycol and Glycerol - Surfactant Type

A

non-ionic

40
Q

Glycol and Glycerol - Emulsion Type

A

W/O

41
Q

Glycol and Glycerol - Examples

A

glycol and glycerol esters of certain higher fatty acids

glycerol monostearate

42
Q

Glycol and Glycerol - pH

A

-

43
Q

Glycol and Glycerol - cations/anions/electrolytes

A

-

44
Q

Glycol and Glycerol - route of administration

A

-

45
Q

Glycol and Glycerol - Miscellaneous

A

strongly hydrophobic nature
poor (W/O) emulsions
mix with little soap (SLS) to get good emulsions

46
Q

Glycol and Glycerol -In situ?

A

-

47
Q

Sorbitan Esters - Surfactant Type

A

Non-ionic

48
Q

Sorbitan Esters - Emulsion Type

A

W/O

49
Q

Sorbitan Esters - Examples

A

Spans

50
Q

Sorbitan Esters - pH

A

-

51
Q

Sorbitan Esters - cations/anions/electrolytes

A

-

52
Q

Sorbitan Esters - route of administration

A

-

53
Q

Sorbitan Esters - Miscellaneous

A

-

54
Q

Sorbitan Esters - in situ?

A

-

55
Q

Polyethylene glycol derivatives of sorbitan esters - surfactant type

A

non-ionic

56
Q

Polyethylene glycol derivatives of sorbitan esters - emulsion type

A

O/W

57
Q

Polyethylene glycol derivatives of sorbitan esters - Examples

A

Tweens

58
Q

Polyethylene glycol derivatives of sorbitan esters - pH

A

-

59
Q

Polyethylene glycol derivatives of sorbitan esters - cations/anions/electrolytes

A

-

60
Q

Polyethylene glycol derivatives of sorbitan esters - route of administration

A

-

61
Q

Polyethylene glycol derivatives of sorbitan esters - miscellaneous

A

-

62
Q

Polyethylene glycol derivatives of sorbitan esters - in situ?

A

-

63
Q

Alkali metal and ammonium soaps - examples

A

salt of long chain fatty acids

sodium stearate

Pharmacy (14 decks)

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