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BCOP > Supportive care > Flashcards

Supportive care Flashcards

1
Q

How long to wait to vaccinate after B-cell directed therapy?

A

6 months

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2
Q

How long to wait to vaccinate after chemo?

A

3 months

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3
Q

How long to wait to vaccinate after T-cell directed therapy? (CAR t or blinatumomab)?

A

1 year/check antigens

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4
Q

What is MOA of blinatumomab

A

BITE therapy - CD3 + tumor cell

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5
Q

What chemo is it okay to have growth factors overlap with?

A

Asparagus add + vincristine (and anything that’s not myelosuppressive)

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6
Q

Which fungal infections do NOT cause a positive Beta-DGlucan?

A

Crypto and mucorales

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7
Q

What is goal trough for voriconazole?

A

> 1-1.5

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8
Q

What are chemitherapies with contraindications to CYP3A4 inhibitors (Eg voriconazole and posaconazole)?

A 
Cyclophosphamide (high-dose)
Vinca alkaloids (vincristine, vinblastine)
Dasatinib
Venetoclax
Midostaurin
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9
Q

What premed are needed with amphotericin B?

A

Hydrocortisone
APAP
Diphenhydramine

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BCOP (2 decks)

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