Superfamily Strongyloidea (Hookworms) Flashcards
Ancylostoma caninum host
dogs…
Ancylostoma brazilinese host
cats and dogs
Ucinaria stenophala host
FOXES, dogs, cats
PPP for A. caninum and U. stenophala
14-21 days (2-3 weeks)
A. caninum route of infection
TRANSMAMMARY, oral, percutaneous (NO transplacental)
U. stenophala route of infection
Oral only (not transmammary, percutaneous)
Traits of L3 in A. caninum
sheathed L3, can arrest development, L3 is infectious
Clinical signs of A. caninum (young and old dogs)
young= acute hemorrhagic anemia
old = chronic hemorrhagic anemia [less common in older animals b/c of acquired immunity]
(and hypersensitivity reactions)
diagnosis A. caninum
clinical signs/hx, fecal egg count
differences in head of Ancylostoma caninum and Ucinaria stenophala
A. caninum = teeth in head
U. stenophala = cutting plates in head
Which hookworms are bloodsuckers (which are not?)
A. caninum = blood sucker (causes anemia b/c blood does not stop when parasite changes spots)
A. brazilinese, U. stenophala = non blood suckers, (protein-losing enteropathy)
Control/Treatment A. caninum
- Benzimidazoles, Ivermectin/Moxidectin, Pyrantel
- Fenbendazole in pregnant bitch
- dry bedding/grass = increased L3 survival
Describe hookworm vaccine
Ag from hookworm gut-> hookworm then ingests Ab from blood of vaccinated host
what does the head of A. caninum release and why?
Lytic factors and anti-coagulants. To help w/ ingesting blood. (areas do not close up when parasite moves)
Pathology of U. stenophala
Not blood sucker (protein-losing enteropathy)
skin infection abortive (penetrates & dies)
Hypersensitivity response (Pedal Dermatitis)
