Supercoiling Flashcards

1
Q

What is supercoiling

A

It is an important topological property of covalently closed circular double-stranded DNA. The circular DNA has a twisted appearance. Bacteria and some viruses also have a circular genome.

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2
Q

What is an important feature of circular duplex DNA

A

The number of times one strand wraps about the other cannot be altered without first cleaving at least one of its polynucleotide strands.

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3
Q

How is this important feature expressed

A

L=T+W : L

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