Summary 9: Antibiotics

Question 1

Enteric bacteria

Answer 1

Antimicrobial sensitivity assay (lots of resistance)

Question 2

Tetanus, botulism

Answer 2

Infection usually transient, antitoxin treatment more important

Question 3

Gas gangrene

Answer 3

Surgical care and protein synthesis inhibiting antibiotics

Question 4

All Rickettsiae (RMSF, typhus, Ehrlichia, Anaplasma)

Answer 4

Doxycycline (they are intracellular)

Question 5

Vibrio cholera

Answer 5

Rehydration, antibiotics are not crucial

Question 6

Heliobacter pylori

Answer 6

Choice of three 10-14 day triple-drug courses

Question 7

Neisseria gonorrhoeae

Answer 7

Ceftriaxone

Question 8

Listeria

Answer 8

Ampicillin (long course)

Question 9

Pseudomonas

Answer 9

Antimicrobial sensitivity assay, antipseudomonal penicillin

Question 10

Syphilis

Answer 10

Penicillin G

Question 11

Lyme disease

Answer 11

Doxycycline 10-30 days (NOT 2 years!!)

Question 12

Tuberculosis

Answer 12

Directly observed therapy with at least four drugs including isoniazid and rifampin; antimicrobial sensitivity assay

Question 13

Chlamydia

Answer 13

Doxycycline (intracellular)

Question 14

Anerobes

Answer 14

Surgical care plus metronidazole

Question 15

Streptococci

Answer 15

Penicillin, erythromycin

Question 16

Staphylococci

Answer 16

Penicillin, oxacillin, methicillin, vancomycin

Question 17

Nosocomial wound infections

Answer 17

Antimicrobial sensitivity testing

Question 18

Pediatric diarrhea

Answer 18

No meds, only rehydration

Question 19

Community-acquired geriatric pneumonia

Answer 19

Take labs
Start levofloxacin
Reassess when labs come back

Question 20

Fungal meningitis

Answer 20

Fluconazole (penetrates spinal fluid well)

Question 21

Systemic fungal infections other than fungal meningitis

Answer 21

Amphotericin B