Substance Use Disorder Flashcards
predisposing factors for child addiction
–genetic
–brain chemistry
–psych factors (stress, impulsive, eating disorders)
–environmental (trauma, substance use)
–starting addictive substance at young age
social components of addiction
–social stigma
–environmental
–peer influence
–dysfunctional family dynamics
–abuse hx
–social maladaptation
–family hx of addiction
–peer pressure
–lack of family involvement
psych aspects of addiction
–stress
–depression
–low self-esteem
–increased need for success/power
–inability to cope
–anxiety
–loneliness
biological aspects of addiction
–genetics
–increased extracellular dopamine
–immature brain development
–acetate
–having another mental health disorder
–being male
cocaine and dopamine
stops molecules that usually mop up excess dopamine
amphetamines and dopamine
push dopamine out of sacs where it is stored
heroin and dopamine
makes dopamine-containing neurons fire more
alcohol and dopamine
helps release more dopamine
back of areas of brain are responsible for what?
areas of emotion, memory, impulse, psychomotor activity
front areas of brain are responsible for what?
areas of executive function, planning, problem solving, judgment, impulse control, organization
difference on brain area between adults and teen decision making
adults=frontal cortex
teens=amygdala
what does alcohol break down into?
acetate
how is acetate digestion different between addicts and non-addicts?
non-addicts: acetate moves through system quickly and exits
addicts: acetate barely processed out so, by staying in the body, it triggers a craving for more acetate, which causes the addict to drink more and more
how does repeated alcohol use lead to tolerance and withdrawal?
–fundamental changes in neurotransmitters
–decreased D2 receptors and decreased dopamine release
what does an addicted brain result in?
–compulsive behaviors
–decreased inhibitory control
–increased impulsivity
–impaired regulation of intentional action
define addiction
a pattern of problematic alcohol use that causes distress and significant impairment
substance intoxication
recent overuse/excessive use of a substance, such as an acute alcohol intoxication, that results in a reversible substance-specific syndrome
physiological changes with alcohol intoxication
–slurring of speech
–poor coordination
–impaired memory
–stupor
–coma
substance withdrawal
symptoms develop when a substance is discontinued abruptly after frequent, heavy, and prolonged substance use
symptoms of substance withdrawal
–anxiety
–irritability
–restlessness
–insomnia
–fatigue
symptoms appearing 6-12 hours after alcohol intake
–minor withdrawal symptoms
–insomnia
–tremulousness
–mild anxiety
–GI upset
–headache
–diaphoresis
–palpitations
–anorexia
symptoms appearing 12-24 hours after alcohol intake
–alcoholic hallucinosis: visual, auditory, or tactile hallucinations
symptoms appearing 24-48 hours after alcohol intake
withdrawal seizures: tonic-clonic
symptoms appearing 48-72 hours after alcohol intake
–alcohol withdrawal delirium (delirium tremens)
symptoms of delirium tremens
–hallucinations
–disorientation
–tachycardia
–hypertension
–low-grade fever
–agitation
–diaphoresis
CIWA components
–N/V
–tremors
–anxiety
–agitation
–paroxysmal sweats
–orientation
–tactile disturbance
–auditory disturbance
–visual disturbance
–headache
CIWA score 0-9
minimal withdrawal
CIWA score 10-19
mild-moderate
CIWA score > 20
severe
meds given for CIWA scoring 8-10+
–chlordiazepoxide
–diazepam
–lorazepam
–thiamine
–phenobarb
–inderal
–clonidine
–mag sulfate
–MVI
–antipsychotics
when should thiamine be given to withdrawal patients?
daily, prior to IV dextrose to prevent Wernicke’s
difference between CIWA and COWS
CIWA = alcohol
COWS = opioids
components of COWS
–resting pulse rate
–sweating
–restlessness
–pupil size
–bone or joint aches
–runny nose or tearing
–GI upset
–tremor
–yawning
–anxiety or irritability
–goosebumps
COWS score 5-12
mild