Substance Use Flashcards
At high levels, what neurotransmitter does alcohol inhibit
Glutamate
What metabolite is thought to accumulate after drinking to cause a hangover?
Acetaldehyde
Will trigger immune response
What is the centre of psychoactive drug activation in the brain?
MCLP
mesocirticolimbic dopamine pathway
What is the intervention being used at American collages to try to curb binge drinking?
BMI
Brief Motivational Intervention
Providing skills to moderate drinking behaviour
What are the three drugs used as a biological intervention to alcohol abuse?
Antabuse
Naltrexone
Acamprosate
What is the abstinence violation effect?
When a small transgression makes a recovering alcoholic feel like they have failed abstinence and so may as well go all the way (guilt…)
How long to develop an opioid addiction?
30 days of continual use
What personality characteristic is associated with substance use?
Sensation seeking
Endorphins are produced by the pituitary gland, what substance are they like?
Opioids - controlling pleasure and pain
When a genetic deviation leads someone to experience less reward and make them vulnerable to drug addiction
Reward deficiency syndrome
Along with the Dopamine theory, which receptors have been implicated in the increased pleasure of substance use?
Opioid
What is the second drug used to assist with Opioid cessation?
Buprenorphine
What substance blocks the presynaptic dopamine transporter? And what does that do?
Cocaine
It prevents the reuptake of dopamine, making more available in the synapse
CBT has been shown to be effective in the treatments of some substance use disorders, what therapy is thought to be better for cocaine addiction?
CM - Contingency Management
What is the part of the brain thought to be implicated in nicotine addiction?
Insula
