Substance P Flashcards
Site of Synthesis of Substance P
CNS and PNS, Neuropeptide
Function of Substance P
Transmit pain (transmits info about tissue damage to CNS) - binds to neurokinin - 1 receptor
Means of Substance P
Acts as a neurotransmitter for pain. Found in all organs of the body.
Substance P _____ heart rate
increases
Substance P is found in brain regions that ________.
regulate emotions
Substance P released is involved in __________ .
neurogenic inflammation - local inflammatory response in certain injury.
Substance P is released from ________ in the skin, muscle, and joints.
sensory nerve fibers
There are ________ concentrations of substance P in the vomiting center in the medulla.
high
Role of substance p in inflammatory disease
respiratory, gastrointestinal, and musculoskeletal system
Inflammatory processes that occur in response to substance p
eczema, fibromyalgia, low back pain, arthritis