Substance P Flashcards

1
Q

Site of Synthesis of Substance P

A

CNS and PNS, Neuropeptide

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2
Q

Function of Substance P

A

Transmit pain (transmits info about tissue damage to CNS) - binds to neurokinin - 1 receptor

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3
Q

Means of Substance P

A

Acts as a neurotransmitter for pain. Found in all organs of the body.

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4
Q

Substance P _____ heart rate

A

increases

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5
Q

Substance P is found in brain regions that ________.

A

regulate emotions

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6
Q

Substance P released is involved in __________ .

A

neurogenic inflammation - local inflammatory response in certain injury.

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7
Q

Substance P is released from ________ in the skin, muscle, and joints.

A

sensory nerve fibers

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8
Q

There are ________ concentrations of substance P in the vomiting center in the medulla.

A

high

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9
Q

Role of substance p in inflammatory disease

A

respiratory, gastrointestinal, and musculoskeletal system

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10
Q

Inflammatory processes that occur in response to substance p

A

eczema, fibromyalgia, low back pain, arthritis

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