Substance abuse Flashcards

1
Q

What are risk factors for drug abuse

A

Genetic
Environment
* socioeconomic factors
* surrounding by those who take drugs
* time of drug use (younger = higher risk)
* personality (low self esteem)
* availability of drugs
* coexisting mental help problems
* peer pressure
* physical and sexual abuse
* early exposure to drugs
* stress

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2
Q

What is the traditional theory on the pattern of addiction

A
  • intense initial intoxiciation
  • development of tolerance
  • escalation in intake
  • profound dysphoria, physical discomfort and somatic withdrawal
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3
Q

What is the ‘reward’ pathway

A
  • when activated by rewarding stimulus, informationt ravels from the VTA to the nucelus accumbens and then up to the prefrontal cortex
  • dopamine mediated transmission allows us to feel pleasure
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4
Q

How do drugs effect neurotransmitters

A

increased dopamina levels - euphoria
decreased levels of serotonin - decreased levels of contentment

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5
Q

Describe the psychodynamic theory

A

two critical elements - disordered emotions and disordered self care
two contributory elements - disordered self esteem and disordered relationships

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6
Q

What does prolonged exposure to drugs of abuse result in

A

addiction via reward pathway
chronic exposure reduces sensitivity of brain to reward system

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7
Q

What are features of drug dependance

A
  • psychological - taking the drug knowing its harmful
  • physical - symptoms if drug not taken
  • withdrawal syndrome - symptoms following sudden withdrawal
  • tolerance - repeated administration means they become less sensitive
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8
Q

What can drugs be divided into

A
  • behavioural classification
  • pharmacodynamic classification
  • legal classification
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9
Q

How can drugs be classed based on behavioural features

A
  • stimulants e.g cocaine
  • opiods
  • sedative
  • anypsychotics
  • antidepressants
  • psychedelics
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10
Q

What are the risks of illicit drug use

A
  • STI
  • BBV
  • TB
  • smoking/alcohol risks
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11
Q

How can drugs be administered

A
  • oral
  • transmucosal
  • inhalation
  • smoking
  • intramuscular
  • IV
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12
Q

What are injection related complications from drug use

A
  • cellulitis
  • abscess
  • thrombophlebitis
  • thrombosis
  • embolism
  • DVT
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13
Q

What are the effects of cannabis

A
  • euphoria
  • slowed thinking and reaction time
  • confusion
  • impaired balance and coordination
  • cough
  • frequent resp infections
  • impared memory and learning
  • increased HR
  • anxiety
  • panic
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14
Q

What are the effects of alcohol

A
  • CNS depressant
  • judgement, concentration and coordination
  • effects are dose related
  • eventually interfere with cerebellar function
  • cause ataxia and motor coordination
  • ultimately unconsciousness
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15
Q

What are signs of substance misuse

A
  • loss of reliability
  • mood and behaviour changes - defensive and angry
  • subjective symptoms
  • requesting specific drugs
  • progressive deterioration in personal appearance and hygiene
  • tremor
  • constricted pupils or dilated
  • puncture marks, scars or pigmentation over veins
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16
Q

What are barriers to accessing dental services for drug misusers

A
  • fear of judgement
  • low priority of OH
  • fear of dentists
  • self medication
  • chaotic lifestyle
  • poor attendance compliance
  • cost
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17
Q

What can help facilitate access for drug misusers

A
  • key workers may be assigned if enrolled in addiction programmes
  • key workers can encourage attendance and accompany px to appointments
18
Q

What are the medical implications of drug misuse

A
  • increased rates of infection
  • general health neglect
  • oral health neglect
  • chronic liver disease in alcohol abuse - impaired drug metabolism and bleeding risk
  • BBV
  • infective endocarditis
  • venous thromboses
19
Q

What are drug misusers at risk of

A
  • crime to fund addiction
  • maxfax injuries
  • sharing of needles - BBV
  • family disruption
  • no address
  • prison
  • risk of withdrawing
  • chaotic lifestyle
20
Q

Why may consent be an issue for this group

A
  • issue for dependent px
  • fluctuating capacity
  • capacity unlikely when under the influence
  • postpone tx
21
Q

What are examples of alcohol related brian damage

A

korsakoffs syndrome
similar to dementia

22
Q

How should we tx plan for these px

A
  • assess px expectation
  • stabilise mouth
  • diet and OHI
  • keep tx as simple as possible during active substance misuse - use ART and SDF
23
Q

How can LA be impacted in cannabis misusers

A

LA with adrenaline can prolong acute tacychardia

24
Q

What problems can LA pose for alcohol misusers

A
  • liver problems
  • lidocaine metabolzied in liver
  • keep doses to minimum
  • use articaine
  • avoid IDB
25
Why can sedation pose a problem to this group
* px may have developed tolerance to sedative drugs so larger doses required - refer to anaesthetist * alcohol and opiod have synergistic effect with sedative agents --> avoid if px actively using substance * GA and IV can trigger relapse * venous access --> collapsing veins
26
What are general dental implications of substance misuse
* rampant caries * periodontal disease * NCTSL * masseteric hypertrophy * hyposalivation * poor OH * opportunistic infections * trauma * oral cancer and mucosal lesions
27
Why are px at risk of necrotizing periodontal diseases
* impaired immune system * stress, BBV, smokers
28
What appointment times should this group be given
morning as less likely to be under the influence high chance of DNA however
29
What are the effect of sedatives in alcohol users
risk of tolerance have an addictive effect
30
Why should GA be avoided in alcohol abusers
* risk of vomiting * risk of inhalation of vomit * can be resistant to GA
31
What drug to recoveirng alcoholics use and what problems does it pose
disulfiram psychotic reaction seen with those who use this drug and metronidazole
32
What are the oral effects of alcohol abuse
* advanced caries * risk of leukoplakia and OC * glossitis * angular stomatitis * RAS * sialosis * rhinophyma * erosion * nocturnal brusism * xerostomia - dehydration
33
What are the systemic manifestations of alcohol abuse
* liver cirrhosis - drug metabolism and bleeding risk * bone marrow suppression: anaemia and thrombocytopenia * impaired wound healing: immunosuppression * avoid use of aspirin and NSAIDs due to gastric erosion * paracetamol safest * avoid metronidazole as inhibits breakdown of acetylaldehyde
34
What are opiates
morphine methadone dihydrocodeine heroin
35
What are the effects of opiates
* euphoria * followed by sedative state * dependant px may find analgesia ineffective in controlling dental pain * never prescribe opiates to this group
36
What are the dental implications of opiate abusers
* trauma * infective endocarditis * oral neglect * drug metabolism
37
Why does methodone pose risk to oral health
* often used long term * contains high sugar content
38
What is dental advise for methodone users
* use a straw * drink water after consumption to prevent regurgiation * dont brush teeth immediately after * engage with dental services * prevention * sugar free suspensions available however pose greater risks
39
What are the risks of cannabis use
* oral cancer * psychosis including schizophrenia * impaired memory * impared cognitive function * xerostomia * caries
40
What are the dental implications of cocaine
* may present with unusual ulceration on gingiva * NCTSL * orofacial pain * long term --> palatal adn nasal septum perforation * interaction with LA - delay tx ideally 24h after administration
41
What is practical advise for tx drug abusers
* dont use adrenaline containing for px taking cocaine, ecstasy and methamphetamines - risk of increasing BP * avoid adrenaline containing LA for cannabis user due to prolonged tachycardia risk * alcohol abusers --> liaise with GP prior to invasive tx . may want some tests