Study Q's - Soska Flashcards

1
Q

Know the various causes of elevated transaminases:

A
  • Alcoholic steatohepatitis
  • Hepatitis - toxic, viral
  • Celiac dz
  • NASH
  • Primary biliary cirrhosis
  • Primary sclerosing cholangitis
  • Wilson’s dz
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2
Q

Know the relationship btw celiac dz and elevated transaminases:

A

x

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3
Q

Understand seroconversion of acute and chronic HBV. Which antigen is persistent in carrier status?

A

x

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4
Q

What are signs and symptoms of HBV and HCV?

A

x

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5
Q

Conventional tx of acute HBV? Chronic?

A

x

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6
Q

Conventional tx of HCV?

A

x

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7
Q

What is the role of antioxidants, and mechanism of action for HBV and HCV?

A

x

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8
Q

How does Silymarin and Silybin-Phosphatidylcholine Complex help in the tx of HBV/HCV?

A

x

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9
Q

What is the role of Glycyrrhiza glabra in the treatment of HBV/HCV?

A

x

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10
Q

What is the role of Low-Dose Naltrexone in tx of HBV and HCV? Mechanism of action?

A

x

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11
Q

Be able to identify the homeopathic picture for the various remedies as it relates to the case/question format.

A

x

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12
Q

What are the risk factors for NAFLD/NASH?

A
  • Obesity
  • Diabetes
  • Insulin resistance
  • Hyperlipidemia
  • Metabolic syndrome
  • Excess fructose consumption
  • Female > Male
  • Surgical procedures - resection, bypass, gastroplasty, IV glucose, etc
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13
Q

Compare fructose and EtOH metabolism:

A

x

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14
Q

Understand the outcome of continual fructose consumption on uric acid levels:

A

Uric acid will be increased due to ATP breakdown to peptides in an effort to maximize phosphate groups for fructose metabolism.

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15
Q

Which pharmaceuticals are risk factors for NASH?

A
  • Ca channel blockers
  • tamoxifen
  • corticosteroids
  • synthetic estrogens
  • aspirin
  • methotrexate
  • valproic acid
  • cocaine
  • AZT
  • amiodarone
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16
Q

How does MSG consumption influence NASH?

A
  • causes increased serum FFAs, TGs, HDL, and insulin.

* increased expression of genes implicated in adipocyte differentiation.

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17
Q

Basic treatment protocol of NASH:

A
  • weight loss
  • regulate insulin, glucose, lipids
  • choleretics, cholegogues
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18
Q

Be able to name at least 4 conditions that would be included in the differential diagnosis in acute cholecystitis.

A

x

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19
Q

Know the difference between the types of stones in found in cholelithiasis and how etiology will influence treatment.

A

x

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20
Q

What are the best methods of imaging for cholelithiasis, in terms of safety, cost, and reliability?

A

v

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21
Q

Which hydrotherapies are best for cholelithiasis, biliary dyskinesia, and cholecystitis, know how they differ, any precautions, or potential contraindications.

A

x

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22
Q

What dietary/lifestyle changes are appropriate for cholelithiasis and biliary dyskinesia?

A

x

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23
Q

Know the role of food allergies, and which ones are commonly seen in cholelithiasis, biliary dyskinesia, and cholecystitis

A

x

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24
Q

What are the primary etiologies for cholelithaisis?

25
Why isn’t lithotripsy used more often as a therapy?
x
26
Understand the role of exercise (or lack thereof) in gallbladder conditions.
x
27
What are the appropriate herbal therapies for cholelithiasis, biliary dyskinesia, and cholecystitis, how do they differ?
x
28
What imaging is best for diagnosing acute pancreatitis?
x
29
Know the possible complications of acute pancreatitis
x
30
Which lab values are indicative of acute pancreatitis?
x
31
Serum amylase: How quickly and long does it stay elevated?
x
32
What ND treatments are appropriate for acute pancreatitis?
* Pancreatic rest * fluid fast * topical COP (no heat) * avoid alcohol * fish oil (9-12g)
33
Know the uses and limitations of chymotrypsin and elastase-1 testing
x
34
What is the etiology of pancreatic insufficiency? a. Celiac disease role in pancreatic insufficiency b. Cow Milk Enteropathy role in pancreatic insufficiency
x
35
Chronic pancreatitis etiology?
x
36
Gold standard testing to diagnose chronic pancreatitis?
ERCP
37
Dietary considerations in chronic pancreatitis?
Inc foods with: vit CADKB12, calcium, folic acid
38
Therapies useful for chronic pancreatitis?
x
39
Pancreatic cancer – why is this condition so often missed?
x
40
Tumor markers that can be helpful diagnosis?
x
41
Primary means of prevention of pancreatic cancer?
* quit smoking * maintain healthy weight * regular exercise * healthy diet (fruit, veg, low animal fat, 10% sat fats) * stress management
42
Treatment options in pancreatic cancer?
x
43
Common non-GI diseases that have sx of constipation?
* Hormonal disorders * Pelvic floor dysfunction * Spinal cord lesions - MS, meningitis, tumors, tabes dorsalis * Peripheral nerve lesion - diabetic neuropathy, Hirschsprung * Chagas * Drugs - particularly opioids, atropine * Muscular weakness
44
Limitations of cathartic herbs in the tx of constipation:
* don't use more than 10 days * potential dependence or electrolyte imbalance * may provoke uterine contractions (cx in pregnancy and lactation)
45
Why is sudden onset constipation concerning?
potential obstruction??
46
Why does Western/SAD diet often result in constipation?
* lack of fiber * poor hydration * overeating
47
What role does ignoring stool urge have on constipation?
Loss of reflex
48
Know the homeopathic remedies for constipation:
? damn gina
49
What changes to BUN levels occur 2° to colon bleeding?
x
50
DDX for colorectal bleeding:
* Diverticulitis/osis * Hemorrhoids * UC/Crohns/IBS/IBD * anal fissure
51
Which imaging is the best in diverticulitis?
Abdominal CT (barium enema may be complementary)
52
Key dietary principles for diverticulosis prevention?
* high-fiber diet * low fat / low beef diet * hydration * short fruit/veg juice fasts * Vit A/B foods * avoid intolerances
53
Acute diverticulitis therapies:
``` Mild - • Initial - rest, liquid diet, oral antibiotics • After a few days - soft, low-fiber diet, psyllium QD • After 1 month - high-fiber diet Severe - (perforation, peritonitis) • Should be admitted to hospital • IV fluids and antibiotics • Bed rest • Nothing by mouth until sx subside ```
54
Treatment protocols for diverticulosis/diverticulitis:
* Abdominal castor oil pack with heat 60 mins TID * Probiotics 50-100bil QD * Water fasting * Yarnell acute div. formula * Monitor Q 12 hours (hospitalize at 48 hrs)
55
What are herbal therapies for colorectal cancers?
``` avena baptisia conium echinacea gentian larrea mahonia phytolacca rumex tarax trifolium viola viscum alba ```
56
Recommendations for colorectal screening schedule:
over 50 years old, or ~40 if FHx colon cancer • pos: repeat w/in 5 yrs • neg: q 10 yrs (opinion varies)
57
Homeopathic remedies for colorectal CA/Polyps:
``` alumen cadmium iod. hydrastis nitric acid ruta scrophularia sepia alcoholus ```
58
Darnell's Acute Diverticulitis Formula:
* Echinacea ang. * Curcuma long. * Populus trem. (aspen) * Glycyrrhiza glabra * Mahonia aq. * Larrea trid. * Foeniculum vulgare