Study Q's - Soska Flashcards
Know the various causes of elevated transaminases:
- Alcoholic steatohepatitis
- Hepatitis - toxic, viral
- Celiac dz
- NASH
- Primary biliary cirrhosis
- Primary sclerosing cholangitis
- Wilson’s dz
Know the relationship btw celiac dz and elevated transaminases:
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Understand seroconversion of acute and chronic HBV. Which antigen is persistent in carrier status?
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What are signs and symptoms of HBV and HCV?
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Conventional tx of acute HBV? Chronic?
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Conventional tx of HCV?
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What is the role of antioxidants, and mechanism of action for HBV and HCV?
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How does Silymarin and Silybin-Phosphatidylcholine Complex help in the tx of HBV/HCV?
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What is the role of Glycyrrhiza glabra in the treatment of HBV/HCV?
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What is the role of Low-Dose Naltrexone in tx of HBV and HCV? Mechanism of action?
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Be able to identify the homeopathic picture for the various remedies as it relates to the case/question format.
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What are the risk factors for NAFLD/NASH?
- Obesity
- Diabetes
- Insulin resistance
- Hyperlipidemia
- Metabolic syndrome
- Excess fructose consumption
- Female > Male
- Surgical procedures - resection, bypass, gastroplasty, IV glucose, etc
Compare fructose and EtOH metabolism:
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Understand the outcome of continual fructose consumption on uric acid levels:
Uric acid will be increased due to ATP breakdown to peptides in an effort to maximize phosphate groups for fructose metabolism.
Which pharmaceuticals are risk factors for NASH?
- Ca channel blockers
- tamoxifen
- corticosteroids
- synthetic estrogens
- aspirin
- methotrexate
- valproic acid
- cocaine
- AZT
- amiodarone
How does MSG consumption influence NASH?
- causes increased serum FFAs, TGs, HDL, and insulin.
* increased expression of genes implicated in adipocyte differentiation.
Basic treatment protocol of NASH:
- weight loss
- regulate insulin, glucose, lipids
- choleretics, cholegogues
Be able to name at least 4 conditions that would be included in the differential diagnosis in acute cholecystitis.
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Know the difference between the types of stones in found in cholelithiasis and how etiology will influence treatment.
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What are the best methods of imaging for cholelithiasis, in terms of safety, cost, and reliability?
v
Which hydrotherapies are best for cholelithiasis, biliary dyskinesia, and cholecystitis, know how they differ, any precautions, or potential contraindications.
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What dietary/lifestyle changes are appropriate for cholelithiasis and biliary dyskinesia?
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Know the role of food allergies, and which ones are commonly seen in cholelithiasis, biliary dyskinesia, and cholecystitis
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What are the primary etiologies for cholelithaisis?
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